Difference between revisions of "Neurofibroma"

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1,160 bytes added ,  14:24, 28 September 2013
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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Neurofibroma_(3).jpg
| Width      =
| Caption    = Neurofibroma. [[H&E stain]].
| Micro      = spindle cells with wavy nuclei without pleomorphism ("shredded carrots"), +/-arranged in fascicles and intermixed with collagen, moderately increased of cellularity, poorly ''or'' well-circumscribed, +/-plexiform growth pattern ("bag of worms"), +/-mast cells (useful)
| Subtypes  = [[plexiform neurofibroma]]
| LMDDx      = [[schwannoma]], [[dermatofibrosarcoma protuberans]], [[ganglioneuroma]], neurotized [[melanocytic nevus]], [[MPNST]]
| Stains    = S-100 +ve, CD34 +ve, EMA +ve/-ve, NF +ve/-ve
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = "bag of worms" appearance (plexiform neurofibroma)
| Grossing  =
| Site      = [[soft tissue lesions|soft tissue]] - [[peripheral nerve sheath tumours]]
| Assdx      =
| Syndromes  = [[neurofibromatosis type 1]]
| Clinicalhx =
| Signs      =
| Symptoms  = [[painful skin lesion]]
| Prevalence = not common
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign if isolated
| Other      =
| ClinDDx    =
}}
'''Neurofibroma''' is an uncommon [[skin]] lesion. This article also includes '''plexiform neurofibroma'''.
'''Neurofibroma''' is an uncommon [[skin]] lesion. This article also includes '''plexiform neurofibroma'''.


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