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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Medial calcific sclerosis -- intermed mag.jpg | |||
| Width = | |||
| Caption = Medial calcific sclerosis. [[H&E stain]]. | |||
| Synonyms = Moenckeberg medial calcific sclerosis, calcific medial sclerosis of Monckeberg, Mönckeberg's arteriosclerosis (also written ''Monckeberg's arteriosclerosis'') | |||
| Micro = calcifications of the tunica media | |||
| Subtypes = | |||
| LMDDx = [[atherosclerosis]] | |||
| Stains = | |||
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| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[blood vessels]] - arteries | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
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| Prognosis = good | |||
| Other = | |||
| ClinDDx = | |||
| Tx = (nothing) | |||
}} | |||
'''Medial calcific sclerosis''' is a type of arteriosclerosis that has no significant clinical impact. | |||
It is also known as '''Moenckeberg medial calcific sclerosis''', '''calcific medial sclerosis of Monckeberg''', and '''Mönckeberg's arteriosclerosis''' (also written '''Monckeberg's arteriosclerosis'''). | |||
==General== | |||
*Usually of no clinical consequence. | |||
==Microscopic== | |||
Features:<ref name=Ref_Klatt7>{{Ref Klatt|7}}</ref> | |||
*Medial calcification (purple irregular stuff on [[H&E stain|H&E]] -- calcium phosphate). | |||
Note: | |||
*Lumen unaffected. | |||
DDx: | |||
*[[Atherosclerosis]] (severe) - intimal hyperplasia with stenosis, calcifications typically in tunica intima. | |||
===Images=== | |||
<gallery> | |||
Image: Medial calcific sclerosis -- low mag.jpg | MCS - low mag. (WC) | |||
Image: Medial calcific sclerosis -- intermed mag.jpg | MCS - intermed. mag. (WC) | |||
Image: Medial calcific sclerosis -- high mag.jpg | MCS - high mag. (WC) | |||
Image: Medial calcific sclerosis - alt -- intermed mag.jpg | MCS - intermed. mag. (WC) | |||
Image: Medial calcific sclerosis - alt -- high mag.jpg | MCS - high mag. (WC) | |||
</gallery> | |||
<gallery> | |||
Image:Calcificatio_atherosclerotica.jpg | MCS. (WC) | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
RIGHT LEG, BELOW KNEE AMPUTATION: | |||
- MINIMAL-TO-MILD LARGE VESSEL ATHEROSCLEROSIS, SEE COMMENT. | |||
- MEDIAL CALCIFIC SCLEROSIS. | |||
- SKIN WITH DERMAL FIBROSIS. | |||
COMMENT: | |||
The sections may not be representative of disease in the distal vascular bed. | |||
</pre> | |||
==See also== | |||
*[[Vascular disease]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Cardiovascular pathology]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] |
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