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| ==Mixed germ cell tumour== | | ==Mixed germ cell tumour== |
| ===General===
| | {{Main|Mixed germ cell tumour}} |
| *60% of GCTs are mixed.
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| Common combinations:
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| # Teratoma + embryonal carcinoma + endodermal sinus tumour (yolk sac tumour) (TEE).
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| # Seminoma + embryonal (SE).
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| # Teratoma + embryonal +(TE).
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| Memory device: ''TEE'' + all combinations have embryonal carcinoma.
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| ===Microscopic===
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| Features:
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| *Depends on components.
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| Notes:
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| *If one cannot identify the component... it is probably yolk sac as this has so many different patterns.
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| ====Images====
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| <gallery>
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| Image:Mixed_germ_cell_tumour_-_intermed_mag.jpg | Mixed GCT - intermed mag. (WC/Nephron)
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| Image:Mixed germ cell tumour - high mag.jpg | Mixed GCT - high mag. (WC/Nephron)
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| </gallery>
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| www:
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| *[http://path.upmc.edu/cases/case192/micro.html Mixed germ cell tumour - several images (upmc.edu)].
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| *[http://path.upmc.edu/cases/case356.html Mixed germ cell tumour - several cases (upmc.edu)].
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| ===IHC===
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| *Beta-hCG +ve - if syncytiotrophoblasts are present.
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| *AFP +ve - a yolk sac tumour component is present.
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| *GFAP +ve - if neuroepithelium is present.
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| ==See also== | | ==See also== |