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COLON (SITE NOT FURTHER SPECIFIED), BIOPSIES: | COLON (SITE NOT FURTHER SPECIFIED), BIOPSIES: | ||
- MODERATE CHRONIC ACTIVE COLITIS. | - MODERATE CHRONIC ACTIVE COLITIS. | ||
- NEGATIVE FOR DYSPLASIA. | - NEGATIVE FOR DYSPLASIA. | ||
- PLEASE SEE COMMENT. | - PLEASE SEE COMMENT. | ||
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COMMENT: | COMMENT: | ||
The sections show colorectal-type mucosa with focal cryptitis and rare neutrophilic crypt | The sections show colorectal-type mucosa with focal cryptitis and rare neutrophilic crypt | ||
abscesses. | abscesses. | ||
Mild architectural changes, suggestive of a chronic colitis, are present. No granulomas are | Mild architectural changes, suggestive of a chronic colitis, are present. No granulomas are | ||
identified. Lymphoid aggregates with germinal centre formation are present in multiple | identified. Lymphoid aggregates with germinal centre formation are present in multiple | ||
fragments. | fragments. The lamina propria has abundant plasma cells throughout the fragments; no | ||
fragments have apparent relative sparing. | |||
Paneth cells are present focally; however, the significance of the paneth cells cannot | |||
determined as the biopsy sites are not known. It is not possible to assess whether there is | |||
of less severe to more severe architectural changes from proximal to distal large bowel, as | a mild gradient of less severe to more severe architectural changes from proximal to distal | ||
may be seen in individuals with ulcerative colitis. | large bowel, as may be seen in individuals with ulcerative colitis. | ||
The findings are compatible with inflammatory bowel disease and chronic active infectious | The findings are compatible with inflammatory bowel disease and chronic active infectious |
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