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Difference between revisions of "Inflammatory skin disorders"
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→Systemic lupus erythematosus: re-work
m (→Vasculitis) |
(→Systemic lupus erythematosus: re-work) |
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*Perivascular neutrophils and lymphocytes. | *Perivascular neutrophils and lymphocytes. | ||
== | ==Lupus erythematosus== | ||
{{Main|Systemic lupus erythematosus}} | {{Main|Systemic lupus erythematosus}} | ||
===General=== | ===General=== | ||
*Systemic disease with multi-organ manifestations. | *Systemic disease with multi-organ manifestations. | ||
SLE has a variety of skin manifestations: | |||
*[[Panniculitis]]. | *[[Panniculitis]]. | ||
*Vacuolar interface dermatitis. | *Vacuolar interface dermatitis. | ||
| Line 116: | Line 116: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features - classic: | ||
*Lymphocytic interface dermatitis.<ref>JAH. 20 February 2009.</ref> | *Lymphocytic interface dermatitis.<ref>JAH. 20 February 2009.</ref> | ||
*Basal layer vacuolation.<ref name=pmid18384217>{{cite journal |author=Crowson AN, Magro CM, Mihm MC |title=Interface dermatitis |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=4 |pages=652–66 |year=2008 |month=April |pmid=18384217 |doi= |url=http://www.archivesofpathology.org/doi/full/10.1043/1543-2165%282008%29132%5B652%3AID%5D2.0.CO%3B2}}</ref> | *Basal layer vacuolation.<ref name=pmid18384217>{{cite journal |author=Crowson AN, Magro CM, Mihm MC |title=Interface dermatitis |journal=Arch. Pathol. Lab. Med. |volume=132 |issue=4 |pages=652–66 |year=2008 |month=April |pmid=18384217 |doi= |url=http://www.archivesofpathology.org/doi/full/10.1043/1543-2165%282008%29132%5B652%3AID%5D2.0.CO%3B2}}</ref> | ||
*Intradermal mucin. | *Intradermal mucin. | ||
*Thin epidermis. | |||
*Compact stratum corneum. | |||
DDx: | |||
*[[Discoid lupus]]. | |||
Images: | Images: | ||