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Difference between revisions of "Non-invasive breast carcinoma"
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Non-invasive breast carcinoma (view source)
Revision as of 15:56, 15 July 2010
, 15:56, 15 July 2010format, refs
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===Size criteria for DCIS=== | ===Size criteria for DCIS=== | ||
DCIS must meet the following size criteria:<ref> | DCIS must meet the following size criteria:<ref name=Ref_BP168>{{Ref BP|168}}</ref> | ||
*2 membrane bound spaces -- OR -- 2 mm. | *2 membrane bound spaces -- OR -- 2 mm. | ||
*If it isn't DCIS... it's atypical ductal hyperplasia (ADH). | *If it isn't DCIS... it's atypical ductal hyperplasia (ADH). | ||
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==FEHUT vs ADH vs DCIS== | ==FEHUT vs ADH vs DCIS== | ||
*Breast duct lumen with too many cells. | *Breast duct lumen with too many cells. | ||
*This is common problem is breast pathology.<ref> | *This is common problem is breast pathology.<ref name=Ref_BP167-8>{{Ref BP|167-8}}</ref> | ||
Definitions: | Definitions: | ||
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*Mnemonic ''CLEAN'' = cell uniformity, luminal spaces, extent/size, arch., nuclei. | *Mnemonic ''CLEAN'' = cell uniformity, luminal spaces, extent/size, arch., nuclei. | ||
** | **Cellular composition: | ||
***EHUT = varied | ***EHUT = varied. | ||
***ADH = focal uniformity | ***ADH = focal uniformity. | ||
***DCIS = uniform. | ***DCIS = uniform. | ||
** | **Lumina: | ||
***EHUT = slits/irregular spaces | ***EHUT = slits/irregular spaces. | ||
***ADH = irregular spaces, no slits | ***ADH = irregular spaces, no slits. | ||
***DCIS = circular "punched-out". | ***DCIS = circular "punched-out". | ||
** | **Extent: | ||
***EHUT = usually lobulocentric | ***EHUT = usually lobulocentric. | ||
***ADH = limited extent. | ***ADH = limited extent. | ||
***DCIS = extensive. | ***DCIS = extensive. | ||
** | **Architecture: | ||
***EHUT = irregular/swirling | ***EHUT = irregular/swirling. | ||
***ADH = DCIS-like | ***ADH = DCIS-like. | ||
***DCIS = DCIS architecture (solid, cribriform, comedo, papillary, micropapillary). | ***DCIS = DCIS architecture (solid, cribriform, comedo, papillary, micropapillary). | ||
** | **Nuclei: | ||
***EHUT = variable | ***EHUT = variable. | ||
***ADH = hyperchromatic + uniform | ***ADH = hyperchromatic + uniform. | ||
***DCIS = evenly spaced. | ***DCIS = evenly spaced. | ||