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(→Microscopic: +micrograph) |
(→Spitz nevus: +pigmented spindle cell nevus of Reed) |
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#*Thick collagen bundles arranged parallel to the skin surface. | #*Thick collagen bundles arranged parallel to the skin surface. | ||
#Features of an [[intradermal nevus]]. | #Features of an [[intradermal nevus]]. | ||
==Pigmented spindle cell nevus | |||
*[[AKA]] ''pigmented spindle cell nevus of Reed''. | |||
===General=== | |||
*Uncommon. | |||
*Women in teens & 20s; location: shoulder, pelvic girdle region. | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP500>{{Ref WMSP|500}}</ref> | |||
*Nests of heavily pigmented spindle cells at dermal-epidermal junction - '''key feature'''. | |||
**Nevoid cells in epidermis & dermis - form "basket weave" pattern | |||
*Well-circumscribed lesion. | |||
Notes: | |||
*No epithelioid nevus cells. | |||
DDx: | |||
*[[Spitz nevus]]. | |||
*[[Melanoma]]. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Pigmented_spindle_cell_nevus_-_low_mag.jpg PSCN - low mag. (WC)]. *[http://commons.wikimedia.org/wiki/File:Pigmented_spindle_cell_nevus_-_2_-_intermed_mag.jpg PSCN - intermed. mag. (WC)]. *[http://www.histopathology-india.net/Reed.htm Reed nevus - collection (histopathology-india.net)]. | |||
==Spitz nevus== | ==Spitz nevus== | ||
*AKA ''epithelioid and spindle-cell nevus''. | *AKA ''epithelioid and spindle-cell nevus''. | ||
=== | ===General=== | ||
*May be very difficult to differentiate from [[melanoma]]. | |||
Epidemiology: | |||
*Children & adolescents. | *Children & adolescents. | ||
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