Mammary hamartoma
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Mammary hamartoma, also breast hamartoma, is an uncommon benign pathology of the breast.
General
- Benign.
- Disordered growth - see hamartoma.
Gross
- Well-circumscribed - key feature.
Microscopic
Features:[1]
- Disordered arrangement of ductal and lobular structures.
- Normal arrangement of cells with in the ductal structures, i.e. myoepithelium and epithelium present.
- Variable features:[2]
- Adipose tissue - predominant.
- Dense fibrosis tissue - predominant.
- Cystic glandular dilation.
Notes:
- If adipose tissue predominates; it may be labeled adenolipoma.[2]
DDx:
- Fibroadenoma - may have adipose tissue.
- Phyllodes tumour - may have adipose tissue.
- Pseudoangiomatous stromal hyperplasia.
- Fibrocystic changes.
Images
IHC
- None - it's a H&E diagnosis.
See also
References
- ↑ O'Malley, Frances P.; Pinder, Sarah E. (2006). Breast Pathology: A Volume in Foundations in Diagnostic Pathology series (1st ed.). Churchill Livingstone. pp. 117. ISBN 978-0443066801.
- ↑ 2.0 2.1 URL: http://surgpathcriteria.stanford.edu/breast/mammhamart/. Accessed on: 4 October 2011.
- ↑ Tse, GM.; Law, BK.; Ma, TK.; Chan, AB.; Pang, LM.; Chu, WC.; Cheung, HS. (Dec 2002). "Hamartoma of the breast: a clinicopathological review.". J Clin Pathol 55 (12): 951-4. PMC 1769817. PMID 12461066. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/.