Kidney metastasis
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Kidney metastasis, also renal metastasis, is a kidney tumour that arose elsewhere and spread to the kidney.
| Kidney metastasis | |
|---|---|
| Diagnosis in short | |
 Metastatic adenocarcinoma involving the kidney. H&E stain. | |
|
| |
| Synonyms | renal metastasis, metastatic disease involving the kidney |
|
| |
| LM | malignant neoplasm - morphology dependent on site of origin, often glandular |
| LM DDx | urothelial carcinoma, primary adenocarcinoma of the renal pelvis, unclassified renal cell carcinoma |
| IHC | PAX8 -ve (usually), vimentin -ve (usually) |
| Gross | mass lesion - classically in cortex close to the glomerular vascular plexus |
| Site | kidney |
|
| |
| Clinical history | +/-history malignancy |
| Symptoms | +/-hematuria |
| Prevalence | rare |
| Prognosis | poor |
| Clin. DDx | renal primary |
General
- Rare.
- History should be compelling.
Clinical:
- +/-Hematuria seen in 12-31% of cases.[1]
Gross
- Typically in cortex close to the glomerular vascular plexus.[2]
Microscopic
Features:
- Malignant neoplasm - morphology dependent on site of origin and type.
Note:
- Urothelial carcinoma may be confused with squamous cell carcinoma of the lung.
DDx:
- Unclassified renal cell carcinoma.
- Primary adenocarcinoma of the renal pelvis[3] - if the tumour is adenocarcinoma.
Images
Case
Kidney metastasis - very low mag.
Kidney metastasis - low mag.
Kidney metastasis - intermed. mag.
Kidney metastasis - high mag.
Kidney metastasis - high mag.
Inflamed kidney - low mag.
Inflamed kidney - intermed. mag.
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See also
References
- ↑ Bailey, JE.; Roubidoux, MA.; Dunnick, NR.. "Secondary renal neoplasms.". Abdom Imaging 23 (3): 266-74. PMID 9569294.
- ↑ 2.0 2.1 Cai, J.; Liang, G.; Cai, Z.; Yang, T.; Li, S.; Yang, J. (2013). "Isolated renal metastasis from squamous cell lung cancer.". Multidiscip Respir Med 8 (1): 2. doi:10.1186/2049-6958-8-2. PMID 23320514.
- ↑ Spires, SE.; Banks, ER.; Cibull, ML.; Munch, L.; Delworth, M.; Alexander, NJ. (Nov 1993). "Adenocarcinoma of renal pelvis.". Arch Pathol Lab Med 117 (11): 1156-60. PMID 8239939.