CD20
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CD20 is a B-cell marker. It is positive in most B-cell lymphoma.
| CD20 | |
|---|---|
| Immunostain in short | |
_CD20.jpg) CD20 staining in a DLBCL. | |
| Similar stains | CD79a, PAX5 |
| Use | B-cell lymphomas |
| Subspeciality | hematopathology |
| Normal staining pattern | membranous |
| Positive | most B-cell lymphomas |
Lymphomas
Negative B cell lymphomas
- Plasmablastic lymphoma.[1]
- ALK+ large B-cell lymphoma.
- Classical Hodgkin's lymphoma.
Abberant faint positive
- T-cell lymphoma/leukemia - rare.[2]
See also
References
- ↑ Teruya-Feldstein, J.; Chiao, E.; Filippa, DA.; Lin, O.; Comenzo, R.; Coleman, M.; Portlock, C.; Noy, A. (Nov 2004). "CD20-negative large-cell lymphoma with plasmablastic features: a clinically heterogenous spectrum in both HIV-positive and -negative patients.". Ann Oncol 15 (11): 1673-9. doi:10.1093/annonc/mdh399. PMID 15520070.
- ↑ Kawano, R.; Niino, D.; Ohshima, K. (2016). "Six Cases of CD20-Positive Adult T-Cell Leukemia.". J Clin Exp Hematop 56 (2): 119-125. doi:10.3960/jslrt.56.119. PMID 27980301.