Syringoma

From Libre Pathology
Revision as of 04:10, 1 November 2024 by Michael (talk | contribs)
Jump to navigation Jump to search

Syringoma is a benign skin lesion.

Syringoma
Diagnosis in short

Syringoma. H&E stain. (WC)

LM bilayered cytologically bland ducts with tadpole-like appearance
Grossing notes unoriented skin ellipse grossing, oriented skin ellipse grossing
Site skin, eyelid - see dermatologic neoplasms

Prognosis benign

General

  • Benign sweat duct tumour.
  • Eccrine differentiation.
  • Classically lower eyelid.[1][2]
  • Typical female - female:male = 6.6:1.[2]

Microscopic

Features:[3]

  • Proliferation of benign ducts with lined by a bilayer (as in normal sweat ducts) with abnormal architecture:
    • Tadpole like appearing ducts.

DDx:

Images

Sign out

A. Right Lower Eyelid Lesion, Biopsy:
	- Benign syringoma.

See also

References

  1. Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 1177. ISBN 978-1416031215.
  2. 2.0 2.1 Lee JH, Chang JY, Lee KH (February 2007). "Syringoma: a clinicopathologic and immunohistologic study and results of treatment". Yonsei Med J 48 (1): 35–40. doi:10.3349/ymj.2007.48.1.35. PMC 2628001. PMID 17326243. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628001/.
  3. URL: http://emedicine.medscape.com/article/1059871-diagnosis. Accessed on: 12 May 2010.
  4. Boecker, W.; Junkers, T.; Reusch, M.; Buerger, H.; Korsching, E.; Metze, D.; Decker, T.; Loening, T. et al. (2012). "Origin and differentiation of breast nipple syringoma.". Sci Rep 2: 226. doi:10.1038/srep00226. PMID 22355740.
  5. Nosrati, N.; Coleman, NM.; Hsu, S. (2008). "Axillary syringomas.". Dermatol Online J 14 (4): 13. PMID 18627735.