Paired box gene 5
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Paired box gene 5, commonly known by the abbreviation PAX5, is a immunostain used in hematopathology.
| Paired box gene 5 | |
|---|---|
| Immunostain in short | |
 PAX5 staining in a classical Hodgkin's lymphoma | |
| Abbreviation | PAX5 |
| Use | B-cell marker, weakly positive in classical Hodgkin's lymphoma |
| Subspeciality | hematopathology |
| Normal staining pattern | nuclear stain |
| Positive | B-cell lymphoma, classical Hodgkin's lymphoma |
Tumours with positive staining
- B-cell lymphomas
- Hodgkin lymphoma
- typically weak in classical Hodgkin's lymphoma
- strong in nodular lymphocyte-predominant Hodgkin's lymphoma
Negative staining
- Plasmablastic neoplasms