Pit1
POU domain, class 1, transcription factor 1 (growth hormone factor 1), also known as POU1F1, abbreviated Pit1, is a cimmunostain used endocrinology.
Pit1 | |
---|---|
Immunostain in short | |
Abbreviation | Pit1 |
Normal staining pattern | nuclear staining |
Positive | Somatotroph, lactotroph adenoma |
General
- Nuclear stain.
Positive
Pit-1 lineage pituitary tumors:[1]
- Somatotroph adenoma.
- Lactotroph adenoma.
- Thyreotropha adenoma.
Occasionally positive
Negative
See also
Wikipedia page: [1]
References
- ↑ Lloyd, RV.; Osamura, RY. (Oct 1997). "Transcription factors in normal and neoplastic pituitary tissues.". Microsc Res Tech 39 (2): 168-81. doi:10.1002/(SICI)1097-0029(19971015)39:2<168::AID-JEMT8>3.0.CO;2-H. PMID 9361268.