Canalicular adenoma
Canalicular adenoma is a rare salivary gland tumour.
Canalicular adenoma | |
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Diagnosis in short | |
Site | salivary gland - usually upper lip |
| |
Signs | mass lesion |
Prevalence | very rare |
General
- Exclusively oral cavity.
Clinical:
- Mass lesion.[1]
Gross
- Classically upper lip - may be buccal mucosa or palate.
Note:
- In one large series of 67 cases:[1]
- Upper lip 69% (47/67).
- Buccal mucosa 25% (17/67).
- Palate 6% (4/67).
Microscopic
Features:
- Cords of tumour ("canals") with beading - characteristic.
- Cystic spaces.
- Tubules.
- Intraluminal squamous balls - common.
DDx:
Images
IHC
- p63 -ve.
- Basal cell adenoma p63 +ve.
See also
References
- ↑ 1.0 1.1 Thompson, LD.; Bauer, JL.; Chiosea, S.; McHugh, JB.; Seethala, RR.; Miettinen, M.; Müller, S. (Jun 2015). "Canalicular adenoma: a clinicopathologic and immunohistochemical analysis of 67 cases with a review of the literature.". Head Neck Pathol 9 (2): 181-95. doi:10.1007/s12105-014-0560-6. PMID 25141970.