Renal oncocytosis

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Renal oncocytosis is the presence of multiple oncocytic lesions within the kidney.[1]

Renal oncocytosis
Diagnosis in short
LM DDx other renal tumours with eosinophilic cytoplasm
IHC characteristic of the histologic appearance - stain like oncocytoma, ChRCC and hybrid tumour
Gross multiple brown kidney nodules (bilateral or unilateral)
Grossing notes total nephrectomy for tumour grossing, partial nephrectomy grossing
Staging kidney tumour staging
Site kidney - see kidney tumours

Syndromes Birt–Hogg–Dubé syndrome

Clinical history +/-chronic renal failure and hemodialysis
Prevalence rare
Radiology multiple renal tumours
Clin. DDx metastatic disease, multifocal renal cell carcinoma

General

Gross

  • Multiple (unilateral or bilateral) brown-coloured nodules.[1]

Microscopic

Features:

DDx:

IHC

See also

References

  1. 1.0 1.1 1.2 1.3 Kuroda, N.; Tanaka, A.; Ohe, C.; Mikami, S.; Nagashima, Y.; Sasaki, T.; Inoue, K.; Hes, O. et al. (Nov 2012). "Review of renal oncocytosis (multiple oncocytic lesions) with focus on clinical and pathobiological aspects.". Histol Histopathol 27 (11): 1407-12. PMID 23018240.