Sarcomatoid carcinoma of the prostate

From Libre Pathology
Revision as of 03:57, 17 July 2015 by Michael (talk | contribs)
Jump to navigation Jump to search

Sarcomatoid carcinoma of the prostate, also sarcomatoid prostatic carcinoma, is a rare subtype of prostatic carcinoma with histomorphologic features suggestive of a sarcoma, and a poor prognosis.

Sarcomatoid carcinoma of the prostate
Diagnosis in short

Sarcomatoid carcinoma of the prostate. H&E stain.
Synonyms sarcomatoid prostatic carcinoma
Subtypes (subtype of prostate carcinoma)
LM DDx sarcoma, sarcomatoid urothelial carcinoma
IHC PSA +ve, keratin +ve
Gross see prostate carcinoma
Grossing notes see prostate carcinoma
Site prostate gland - see prostate carcinoma
Syndromes see prostate carcinoma
Clinical history typically have history of conventional prostate carcinoma
Prevalence uncommon
Prognosis poor
Clin. DDx see prostate carcinoma
Treatment see prostate carcinoma

General

  • Rare.[1]
  • Poor prognosis - estimated 20% mortality at one year.[1]

Microscopic

Features:[2]

DDx:

Images

Sarcomatoid carcinoma:

  • SPC - low mag.

  • SPC - intermed. mag.

  • SPC - high mag.

  • SPC - very high mag.

  • SPC - intermed. mag.

  • SPC - high mag.

  • SPC - very high mag.

Accompanying (conventional) prostatic carcinoma:

  • SCP - intermed. mag.

  • SCP - intermed. mag.

IHC

Features - typical:[2]

  • PSA +ve.
  • Keratin +ve.

See also

References

  1. ↑ 1.0 1.1 Hansel, DE.; Epstein, JI. (Oct 2006). "Sarcomatoid carcinoma of the prostate: a study of 42 cases.". Am J Surg Pathol 30 (10): 1316-21. doi:10.1097/01.pas.0000209838.92842.bf. PMID 17001164.
  2. ↑ 2.0 2.1 Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 77 & 80. ISBN 978-0443066771.
Retrieved from "https://librepathology.org/w/index.php?title=Sarcomatoid_carcinoma_of_the_prostate&oldid=38867"