Angiomyofibroblastoma
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Angiomyofibroblastoma is rare uncommon soft tissue lesion of the vulva.
General
Clinical DDx:
Gross
Microscopic
Features:[3]
- Hypercellular zones and hypocellular edematous zones.
- Small blood vessels (~20 micrometers) - no large blood vessels - key feature.
- Myxoid stroma - key feature.
- Small stellate cell/spindle cells without significant nuclear atypia.
DDx:
- Aggressive angiomyxoma - less cellular, large blood vessels.
Images
www:
IHC
- SMA +ve.
- S-100 -ve.
- Actin -ve.
- CD34 -ve.
See also
References
- ↑ 1.0 1.1 Ding, G.; Yu, Y.; Jin, M.; Xu, J.; Zhang, Z. (Feb 2014). "Angiomyofibroblastoma-like tumor of the scrotum: A case report and literature review.". Oncol Lett 7 (2): 435-438. doi:10.3892/ol.2013.1741. PMID 24396463.
- ↑ Butt, Z.; Slatnik, J.; Estey, EP. (Dec 2013). "Robotic assisted laparoscopic excision of a pelvic angiomyofibroblastoma-like tumor.". Can J Urol 20 (6): 7067-9. PMID 24331351.
- ↑ Fletcher, CD.; Tsang, WY.; Fisher, C.; Lee, KC.; Chan, JK. (Apr 1992). "Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma.". Am J Surg Pathol 16 (4): 373-82. PMID 1314521.