Eosinophilic gastritis

Eosinophilic gastritis, abbreviated EG, is an uncommon inflammatory process of stomach characterized by abundant eosinophils.

General

• Rare.

Gross

• +/-Snakeskin appearance.

DDx:

• Portal hypertensive gastropathy.

Microscopic

Features:

• Abundant eosinophils -- >=127 eosinophils/mm².
  • 30 eosinophils/HPF, if the field diameter of 1 HPF is 0.55 mm.

Notes:

• Normal range:
  • <38 eosinophils/mm².
    • Typically ~16 eosinophils/mm².
• Mild eosinophilia is seen in:
  • Crohn's disease ~ 31 eosinophils/mm² (range: 0-203 eosinophils/mm²).
  • Helicobacter gastritis ~ 25 eosinophils/mm² (range: 0-219 eosinophils/mm²).

DDx:

• Chronic gastritis.
• Helicobacter gastritis.
• Crohn's disease - see inflammatory bowel disease and the stomach.

See also

• Stomach.
• Eosinophilic colitis.
• Eosinophilic esophagitis.