Tubulocystic carcinoma of the kidney

From Libre Pathology
Revision as of 18:33, 3 November 2013 by Michael (talk | contribs) (tweak)
Jump to navigation Jump to search

Tubulocystic carcinoma of the kidney, abbreviated TCCK, is a very rare kidney tumour.

It is also known as low-grade collecting duct carcinoma.[1]

General

  • Not in the WHO classification of renal tumours - as of 2013.[2]
  • Rare <1% - in a series of 615 cases.
  • Males:Females ~ 7:1.[1]
  • Prognosis - probably favourable.[1]

Gross

  • Bubble wrap-like appearance - due to the cystic nature.[1]

Microscopic

Features:.[1]

  • Cysts of variable size lined by a single layer of epithelium that has a:
    • Cuboidal, flat, or hobnail morphology.
    • Eosinophilic cytoplasm.
    • Large nuclei with prominent nucleoli.
  • +/-Fibrotic stroma.

DDx:

IHC

Features:[2]

  • CD10 +ve.
  • RCC +ve.
  • Vimentin +ve.
  • AMACR +ve.

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Amin, MB.; MacLennan, GT.; Gupta, R.; Grignon, D.; Paraf, F.; Vieillefond, A.; Paner, GP.; Stovsky, M. et al. (Mar 2009). "Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma.". Am J Surg Pathol 33 (3): 384-92. doi:10.1097/PAS.0b013e3181872d3f. PMID 19011562.
  2. ↑ 2.0 2.1 Alexiev, BA.; Drachenberg, CB. (May 2013). "Tubulocystic carcinoma of the kidney: a histologic, immunohistochemical, and ultrastructural study.". Virchows Arch 462 (5): 575-81. doi:10.1007/s00428-013-1398-0. PMID 23525677.
Retrieved from "https://librepathology.org/w/index.php?title=Tubulocystic_carcinoma_of_the_kidney&oldid=25455"