Colitis cystica profunda
Colitis cystica profunda, abbreviated CCP, a very rare gastrointestinal pathology.
| Colitis cystica profunda | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | mucin filled cysts in submucosa or deeper |
| LM DDx | well-differentiated colorectal adenocarcinoma, mucinous adenocarcinoma |
| Site | colon and rectum, usu. distal |
|
| |
| Associated Dx | cap polyposis |
| Prevalence | very rare (case reports) |
| Endoscopy | polypoid lesion(s) |
| Prognosis | good, benign |
| Clin. DDx | other polypoid lesions |
General
- Very rare ~ 200 cases reported.[1]
- Benign - may mimic adenocarcinoma.[2]
- Has been reported in conjunction with colonic adenocarcinoma.[3]
- The same process in the small bowel is enteritis cystica profunda.[1]
- Association with cap polyposis.[4]
Gross
Features:[5]
- Colon and rectum - usu. distal location.
- Typically focal.
- Polypoid lesions.
Microscopic
Features:
DDx:
- Well-differentiated colorectal adenocarcinoma.[2]
- Metastatic mucinous adenocarcinoma.
Image:
See also
References
- ↑ 1.0 1.1 Dolar, E.; Kiyici, M.; Yilmazlar, T.; Gürel, S.; Nak, SG.; Gülten, M. (Sep 2007). "Colitis cystica profunda.". Turk J Gastroenterol 18 (3): 206-7. PMID 17891698.
- ↑ 2.0 2.1 2.2 Kayaçetin, E.; Kayaçetin, S.. "Colitis cystica profunda simulating rectal carcinoma.". Acta Chir Belg 105 (3): 306-8. PMID 16018526.
- ↑ Mitsunaga, M.; Izumi, M.; Uchiyama, T.; Sawabe, A.; Tanida, E.; Hosono, K.; Abe, T.; Shirahama, K. et al. (Mar 2009). "Colonic adenocarcinoma associated with colitis cystica profunda.". Gastrointest Endosc 69 (3 Pt 2): 759-60; discussion 760-1. doi:10.1016/j.gie.2008.12.240. PMID 19251024.
- ↑ Arana, R.; Fléjou, JF.; Parc, Y.; El-Murr, N.; Cosnes, J.; Svrcek, M. (Sep 2013). "Cap polyposis and colitis cystica profunda: a rare association.". Histopathology. doi:10.1111/his.12292. PMID 24118052.
- ↑ 5.0 5.1 Higuera Alvarez, R.; García, Jde L.; San Miguel, G.; Castro, B. (Apr 2008). "[Colitis cystica profunda].". Rev Esp Enferm Dig 100 (4): 240-2. PMID 18563984.
- ↑ 6.0 6.1 Qayed, E.; Srinivasan, S.; Wehbi, M. (Jan 2011). "A case of colitis cystica profunda in association with diverticulitis.". Am J Gastroenterol 106 (1): 172-3. doi:10.1038/ajg.2010.374. PMID 21212765.