Phosphaturic mesenchymal tumour

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Phosphaturic mesenchymal tumor is a rare tumour. It is also known as phosphaturic mesenchymal tumour, mixed connective tissue type, abbreviated PMTMCT.

Phosphaturic mesenchymal tumour
Diagnosis in short
Site soft tissue, bone

Blood work low serum phosphate

General

  • Extremely rare.
  • Hypophosphatemia.[1]
  • Most common cause of oncogenic osteomalacia (tumour-induced osteomalacia).[2]

Gross

Microscopic

Features:[2]

  • Spindle cells without atypia in a fibrillary matrix.
  • Osteoclast-type giant cells.

References

  1. Papierska, L.; Ćwikła, JB.; Misiorowski, W.; Rabijewski, M.; Sikora, K.; Wanyura, H. (2013). "Unusual case of phosphaturic mesenchymal tumor.". Pol Arch Med Wewn 123 (5): 255-6. PMID 23722193.
  2. 2.0 2.1 William, J.; Laskin, W.; Nayar, R.; De Frias, D. (Aug 2012). "Diagnosis of phosphaturic mesenchymal tumor (mixed connective tissue type) by cytopathology.". Diagn Cytopathol 40 Suppl 2: E109-13. doi:10.1002/dc.21647. PMID 22927293.
  3. Jiang, Y.; Xia, WB.; Xing, XP.; Silva, BC.; Li, M.; Wang, O.; Zhang, HB.; Li, F. et al. (Sep 2012). "Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature.". J Bone Miner Res 27 (9): 1967-75. doi:10.1002/jbmr.1642. PMID 22532501.