Radiation oncology
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Radiation oncology is a place where people go after the pathologist has diagnosed it as cancer.
Dose
- Measure with several units.
Gray
- Abbreviated Gy.
- Energy/mass.
Sievert
- Abbreviated Sv.
- "Biologic effect"/mass.[1]
Where:
- X = fiddle factor for type of tissue and type of radiation.
- dose = dose in Gray.
Typical doses
Single dose:[1]
- <0.5 Gy no histologic change.
- 1-2 Gy proliferating cells die.
- 10 Gy overt necrosis.
Total:
- Solid tumours ~ 60 to 80 Gy.
- Lymphoma ~ 20 to 40 Gy.
Biology
- DNA damage is thought to depend on reactive oxygen species.
- Therefore, poorly oxygenated and poorly vascularized tissues are less sensitive to radiation exposures/treatments.[1]
See also
References
- ↑ 1.0 1.1 1.2 Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 222. ISBN 978-1416054542.