Villous hypoplasia

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Villous hypoplasia, also distal villous hypoplasia, is pathology of the placenta associated with intrauterine growth restriction.

It is also known as terminal villus deficiency.[1]

General

  • Associated with IUGR.[1][2]
  • Atypical Doppler flow measurements: high Doppler resistance index.[1]

Microscopic

Features:[1]

  • Small, round villi (30-60 micrometers).
  • "Long" villi (due to lack of branching).
  • Absence of syncytial knotts.
  • Wide intervillous space.

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PLACENTA AND MEMBRANES, BIRTH:
- SMALL PLACENTA FOR GESTATIONAL AGE (265 GRAMS - TRIMMED , POST FIXATION).
- FETAL MEMBRANES WITHIN NORMAL LIMITS.
- THREE-VESSEL CORD WITHIN NORMAL LIMITS.
- PLACENTAL DISC WITH VILLOUS HYPOPLASIA.

COMMENT:
THE PLACENTAL FINDINGS ARE COMPATIBLE WITH INTRAUTERINE GROWTH RESTRICTION.

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Baergen, Rebecca N. (2011). Manual of Pathology of the Human Placenta (2nd ed.). Springer. pp. 346. ISBN 978-1441974938.
  2. ↑ Fitzgerald, B.; Kingdom, J.; Keating, S. (May 2012). "Distal villous hypoplasia.". Diagnostic Histopathology 18 (5): 195-200. doi:10.1016/j.mpdhp.2012.02.005.
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