Talk:Squamous intraepithelial lesion of the uterine cervix

UTERINE CERVIX, BIOPSY:
- SQUAMOUS INTRAEPITHELIAL LESION, FAVOUR HIGH-GRADE -- SMALL FOCUS, SEE COMMENT.
- BENIGN ENDOCERVICAL EPITHELIUM PRESENT.

COMMENT:
The cytology has intermediate features.

A p16 immunostain strongly marks the full thickness of the thin (abnormal) squamous
epithelium seen in the plane of section, and a Ki-67 focally shows positive superficial cells. These findings favour the presence of a high-grade squamous intraepithelial lesion (HSIL).

A re-biopsy with close follow-up could be considered.