Intestinal metaplasia of the gallbladder
Jump to navigation
Jump to search
Intestinal metaplasia of the gallbladder | |
---|---|
Diagnosis in short | |
Gallbladder with intestinal metaplasia. H&E stain. | |
LM DDx | gallbladder mucosa with goblet cells |
Stains | Alcian blue stain +ve |
Site | gallbladder |
| |
Associated Dx | chronic cholecystitis |
Prognosis | benign, increased risk of carcinoma |
Intestinal metaplasia of the gallbladder is a pathology of the gallbladder associated with an increased risk of gallbladder carcinoma.
It is also known as gallbladder intestinal metaplasia.
General
Significance:
- Increased risk of carcinoma.[1]
Gross
- No specific changes.
Microscopic
Features:[2]
- Goblet cells - key feature.
- +/-Paneth cells.[3]
Note:
- Often accompanied by antral type metplasia.
- Gastric antral-type epithelium - may form glands.
DDx:
Images
www:
Sign out
GALLBLADDER, CHOLECYSTECTOMY: - INTESTINAL METAPLASIA OF THE GALLBLADDER, FOCAL. - CHRONIC CHOLECYSTITIS. - CHOLELITHIASIS. - NEGATIVE FOR DYSPLASIA.
See also
References
- ↑ Duarte, I.; Llanos, O.; Domke, H.; Harz, C.; Valdivieso, V. (Sep 1993). "Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution, and probability of detection in routine histologic samples.". Cancer 72 (6): 1878-84. PMID 8364865.
- ↑ Albores-Saavedra, J.; Nadji, M.; Henson, DE.; Ziegels-Weissman, J.; Mones, JM. (Jun 1986). "Intestinal metaplasia of the gallbladder: a morphologic and immunocytochemical study.". Hum Pathol 17 (6): 614-20. PMID 2872152.
- ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 1789. ISBN 978-0781740517.
- ↑ Cite error: Invalid
<ref>
tag; no text was provided for refs namedpmid15737036