Progesterone receptor
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| Progesterone receptor | |
|---|---|
| Immunostain in short | |
 PR staining in pulmonary meningothelial-like nodule. | |
| Abbreviation | PgR |
| Normal staining pattern | nuclear staining |
| Positive | many breast carcinomas, pulmonary meningothelial-like nodule |
Progesterone receptor, abbreviated PgR, is a common immunostain.
General
- Nuclear stain.
Positive
- Breast carcinoma - most.
- Neuroendocrine carcinoma of the breast.[1]
- Meningioma - most except for fibromatous subtype.[2][3]
- Pulmonary meningothelial-like nodule.
Occasionally positive
Lung adenocarcinoma.[4] Synovial sarcoma.[5]
Negative
See also
References
- ↑ Lavigne, M.; Menet, E.; Tille, JC.; Lae, M.; Fuhrmann, L.; Bonneau, C.; Deniziaut, G.; Melaabi, S. et al. (Jan 2018). "Comprehensive clinical and molecular analyses of neuroendocrine carcinomas of the breast.". Mod Pathol 31 (1): 68-82. doi:10.1038/modpathol.2017.107. PMID 28884749.
- ↑ Schnegg, JF.; Gomez, F.; LeMarchand-Beraud, T.; de Tribolet, N. (Jun 1981). "Presence of sex steroid hormone receptors in meningioma tissue.". Surg Neurol 15 (6): 415-8. PMID 7280951.
- ↑ Tilzer, LL.; Plapp, FV.; Evans, JP.; Stone, D.; Alward, K. (Feb 1982). "Steroid receptor proteins in human meningiomas.". Cancer 49 (4): 633-6. PMID 7055777.
- ↑ Berardi, R.; Morgese, F.; Santinelli, A.; Onofri, A.; Biscotti, T.; Brunelli, A.; Caramanti, M.; Savini, A. et al. (Dec 2016). "Hormonal receptors in lung adenocarcinoma: expression and difference in outcome by sex.". Oncotarget 7 (50): 82648-82657. doi:10.18632/oncotarget.12244. PMID 27690341.
- ↑ Boulagnon-Rombi, C.; Fleury, C.; Fichel, C.; Lefour, S.; Marchal Bressenot, A.; Gauchotte, G. (04 2017). "Immunohistochemical Approach to the Differential Diagnosis of Meningiomas and Their Mimics.". J Neuropathol Exp Neurol 76 (4): 289-298. doi:10.1093/jnen/nlx008. PMID 28340171.