Porocarcinoma
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Porocarcinoma is a rare malignant skin tumour that has an aggressive behaviour.[1]
It is also known as eccrine porocarcinoma', abbreviated EPC.
General
Clinical - based on meta-analysis of 453 cases:
- No predominance males versus females.
- Aggressive behaviour >30% of cases have metastases at presentation - typically to lymph nodes.
Treatment:
- Surgery,
Gross
- Mass or nodule - typically head and neck (40% of cases) or lower extremity (34% of cases).[1]
Microscopic
Features:
DDx:[2]
- Basal cell carcinoma.
- Squamous cell carcinoma.
- Pyogenic granuloma.
- Verruca vulgaris.
- Adenocarcinoma.
- Malignant melanoma - desmoplastic and nodular variants.
Images
See also
References
- ↑ 1.0 1.1 Salih, AM.; Kakamad, FH.; Baba, HO.; Salih, RQ.; Hawbash, MR.; Mohammed, SH.; Othman, S.; Saeed, YA. et al. (Aug 2017). "Porocarcinoma; presentation and management, a meta-analysis of 453 cases.". Ann Med Surg (Lond) 20: 74-79. doi:10.1016/j.amsu.2017.06.027. PMID 28721214.
- ↑ 2.0 2.1 2.2 Abarzúa, Á.; Álvarez-Véliz, S.; Moll-Manzur, C.. "Concomitant poroma and porocarcinoma.". An Bras Dermatol 92 (4): 550-552. doi:10.1590/abd1806-4841.20175719. PMID 28954110.
- ↑ Riera-Leal, L.; Guevara-Gutiérrez, E.; Barrientos-García, JG.; Madrigal-Kasem, R.; Briseño-Rodríguez, G.; Tlacuilo-Parra, A. (2015). "Eccrine porocarcinoma: epidemiologic and histopathologic characteristics.". Int J Dermatol 54 (5): 580-6. doi:10.1111/ijd.12714. PMID 25515648.