Gallbladder cholesterolosis

Gallbladder cholesterolosis
Diagnosis in short
Gallbladder cholesterolosis. H&E stain.
LM	abundant foamy macrophages in the lamina propria, +/-papillary hyperplasia
LM DDx	cholesterol polyp of gallbladder
Gross	gallbladder mucosa with strawberry-like texture
Site	gallbladder
Associated Dx	chronic cholecystitis, obesity, cholelithiasis
Clinical history	biliary colic - due to chronic cholecystitis
Prevalence	common
Prognosis	benign

Gallbladder cholesterolosis, also known simply as cholesterolosis, is a common gallbladder pathology associated with chronic cholecystitis.

Informally, gallbladder cholesterolosis is known as strawberry gallbladder.

General

• Common in chronic cholecystitis.
• Associated with yellow gallstones (cholesterol type gallstones).

Gross

Features:

• Mucosa has strawberry-like appearance.
  • The similarity is in the surface texture.
  • The colour (yellow) is not strawberry-like.

Image

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  Gallbladder cholesterolosis. (WC/euthman)

Microscopic

Features:

• Numerous foamy macrophages in the lamina propria.
• +/-Papillary hyperplasia.

DDx:

• Cholesterol polyp of gallbladder - polypoid shape.

Image

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  Cholesterolosis - intermed. mag. (WC)

• 

  Cholesterolosis. (WC)

www:

• Papillary hyperplasia (surgpath4u.com).

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GALLBLADDER, CHOLECYSTECTOMY:
- CHRONIC CHOLECYSTITIS WITH CHOLESTEROLOSIS.
- CHOLELITHIASIS.

GALLBLADDER, CHOLECYSTECTOMY:
- CHRONIC CHOLECYSTITIS WITH FOCAL FOAMY MACROPHAGES IN LAMINA PROPRIA.
- CHOLELITHIASIS.

See also

• Chronic cholecystitis.
• Gallbladder.