Sarcomatoid carcinoma of the prostate

Sarcomatoid prostate carcinoma is a rare subtype of prostatic carcinoma.

General

• Rare.
• Poor prognosis - estimated 20% mortality at one year.

Microscopic

Features:

• Biphasic tumour:
  1. Spindle cells (sarcomatous component).
     • May include components of: osteosarcoma, chondrosarcoma and/or rhabdomyosarcoma.
  2. Glandular component (like conventional prostate carcinoma).

IHC

Features - typical:

• PSA +ve.
• Keratin +ve.

See also

• Prostate cancer.
• Carcinosarcoma.
• Sarcomatoid carcinoma.