Intestinal metaplasia of the gallbladder

From Libre Pathology
Revision as of 02:02, 15 December 2013 by Michael (talk | contribs) (→‎Images)
Jump to navigation Jump to search
Intestinal metaplasia of the gallbladder
Diagnosis in short

Gallbladder with intestinal metaplasia. H&E stain.
LM DDx gallbladder mucosa with goblet cells
Stains Alcian blue stain +ve
Site gallbladder
Associated Dx chronic cholecystitis
Prognosis benign, increased risk of carcinoma

Intestinal metaplasia of the gallbladder is a pathology of the gallbladder associated with an increased risk of gallbladder carcinoma.

It is also known as gallbladder intestinal metaplasia.

General

Significance:

  • Increased risk of carcinoma.[1]

Gross

  • No specific changes.

Microscopic

Features:[2]

Note:

  • Often accompanied by antral type metplasia.
    • Gastric antral-type epithelium - may form glands.

DDx:

Images

  • GB with IM - low mag.

  • GB with IM - intermed. mag.

  • GB with IM - high mag.

www:

Sign out

GALLBLADDER, CHOLECYSTECTOMY: 
- INTESTINAL METAPLASIA OF THE GALLBLADDER, FOCAL. 
- CHRONIC CHOLECYSTITIS. 
- CHOLELITHIASIS.
- NEGATIVE FOR DYSPLASIA.

See also

References

  1. ↑ Duarte, I.; Llanos, O.; Domke, H.; Harz, C.; Valdivieso, V. (Sep 1993). "Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution, and probability of detection in routine histologic samples.". Cancer 72 (6): 1878-84. PMID 8364865.
  2. ↑ Albores-Saavedra, J.; Nadji, M.; Henson, DE.; Ziegels-Weissman, J.; Mones, JM. (Jun 1986). "Intestinal metaplasia of the gallbladder: a morphologic and immunocytochemical study.". Hum Pathol 17 (6): 614-20. PMID 2872152.
  3. ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 1789. ISBN 978-0781740517.
  4. ↑ Mukhopadhyay, S.; Landas, SK. (Mar 2005). "Putative precursors of gallbladder dysplasia: a review of 400 routinely resected specimens.". Arch Pathol Lab Med 129 (3): 386-90. doi:10.1043/1543-2165(2005)129386:PPOGDA2.0.CO;2. PMID 15737036.
Retrieved from "https://librepathology.org/w/index.php?title=Intestinal_metaplasia_of_the_gallbladder&oldid=26746"