Diagnostic size cutoffs

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Diagnostic size cutoffs are cutoffs which (in part) define a diagnosis and are seen in a number of places in pathology. They are usually somewhat arbitrary by their nature; however, they often make sense from a biologic big picture/management perspective. It doesn't make sense to treat ADH and low-grade DCIS the same, as their behaviour is different.

In pathology, size matters. With other things equal, in the context of how tumours are currently evaluated, big tumours do worse than small tumours.

Precursor Cutoff for precursor Cancer Notes
Papillary adenoma of the kidney <=0.5 cm Papillary_renal_cell_carcinoma -
Atypical alveolar hyperplasia <5 mm[1] Adenocarcinoma in situ of the lung -
Atypical ductal hyperplasia <2mm Low-grade ductal carcinoma in situ Different criterion for lesions in an intraductal papilloma
Atypical ductal hyperplasia in an intraductal papilloma <3mm Low-grade ductal carcinoma in situ in an intraductal papilloma -

See also

References

  1. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 114. ISBN 978-0781765275.