Difference between revisions of "Sickle cell disease"
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'''Sickle cell disease''' is a heritable [[haematopathology|haematologic]] disorder associated with serious pathologies. | '''Sickle cell disease''', also '''sickle cell [[anemia]], is a heritable [[haematopathology|haematologic]] disorder associated with serious pathologies. | ||
==Liver== | ==Liver== | ||
Revision as of 14:43, 30 July 2011
Sickle cell disease, also sickle cell anemia, is a heritable haematologic disorder associated with serious pathologies.
Liver
Main article: Liver
- Cirrhosis and liver failure.[1]
Spleen
Main article: Spleen
- It may lead to auto infarction - result in hypofunction.
- Splenectomy have increased risk from polysaccharide encapsulated bacteria, i.e. Neisseria meningitis, Haemophilus influenzae, and Streptococcus pneumoniae.
Gallbladder
Main article: Gallbladder
- Pigment stones.
Kidney
- Renal medullary carcinoma associated with sickle cell trait (heterozygotes for the sickle cell allele).[2]
See also
References
- ↑ Hurtova, M.; Bachir, D.; Lee, K.; Calderaro, J.; Decaens, T.; Kluger, MD.; Zafrani, ES.; Cherqui, D. et al. (Apr 2011). "Transplantation for liver failure in patients with sickle cell disease: challenging but feasible.". Liver Transpl 17 (4): 381-92. doi:10.1002/lt.22257. PMID 21445921.
- ↑ Davis CJ, Mostofi FK, Sesterhenn IA (January 1995). "Renal medullary carcinoma. The seventh sickle cell nephropathy". Am. J. Surg. Pathol. 19 (1): 1–11. PMID 7528470.