Difference between revisions of "Nodal nevus"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = capsular nevus, benign nevus cells in lymph node | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = [[malignant melanoma]] | |||
| Stains = | |||
| IHC = S-100 +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = usually not apparent | |||
| Grossing = | |||
| Staging = | |||
| Site = [[lymph node]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = none | |||
| Symptoms = | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[lymph node metastasis]] | |||
| Tx = none | |||
}} | |||
'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal | last1 = Lee | first1 = JJ. | last2 = Granter | first2 = SR. | last3 = Laga | first3 = AC. | last4 = Saavedra | first4 = AP. | last5 = Zhan | first5 = Q. | last6 = Guo | first6 = W. | last7 = Xu | first7 = S. | last8 = Murphy | first8 = GF. | last9 = Lian | first9 = CG. | title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. | journal = Mod Pathol | volume = 28 | issue = 2 | pages = 218-29 | month = Feb | year = 2015 | doi = 10.1038/modpathol.2014.99 | PMID = 25081754 }}</ref> | '''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal | last1 = Lee | first1 = JJ. | last2 = Granter | first2 = SR. | last3 = Laga | first3 = AC. | last4 = Saavedra | first4 = AP. | last5 = Zhan | first5 = Q. | last6 = Guo | first6 = W. | last7 = Xu | first7 = S. | last8 = Murphy | first8 = GF. | last9 = Lian | first9 = CG. | title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. | journal = Mod Pathol | volume = 28 | issue = 2 | pages = 218-29 | month = Feb | year = 2015 | doi = 10.1038/modpathol.2014.99 | PMID = 25081754 }}</ref> | ||
Revision as of 03:49, 11 June 2019
| Nodal nevus | |
|---|---|
| Diagnosis in short | |
|
| |
| Synonyms | capsular nevus, benign nevus cells in lymph node |
| LM DDx | malignant melanoma |
| IHC | S-100 +ve |
| Gross | usually not apparent |
| Site | lymph node |
|
| |
| Signs | none |
| Prevalence | rare |
| Prognosis | benign |
| Clin. DDx | lymph node metastasis |
| Treatment | none |
Nodal nevus, also capsular nevus, is benign lymph node findings that can be mistaken for malignant melanoma.[1]
Nevus in lymph node redirects here.
General
- Lymph node metastases from cutaneous melanoma are common and seen in approximately 20% of cases.[2]
- May be confused with malignant melanoma.[3]
Gross
- Usually not apparent.
Microscopic
Features:
- Nevus cells with bland cytomorphology.
- Lack size variation, nucleoli.
- Non-proliferative.
Note:
- No standardized criteria.[3]
DDx:
IHC
Features:[3]
- S-100 +ve.
References
- ↑ Lee, JJ.; Granter, SR.; Laga, AC.; Saavedra, AP.; Zhan, Q.; Guo, W.; Xu, S.; Murphy, GF. et al. (Feb 2015). "5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies.". Mod Pathol 28 (2): 218-29. doi:10.1038/modpathol.2014.99. PMID 25081754.
- ↑ Prieto, VG. (09 2017). "Sentinel Lymph Nodes in Cutaneous Melanoma.". Clin Lab Med 37 (3): 417-430. doi:10.1016/j.cll.2017.05.002. PMID 28802493.
- ↑ 3.0 3.1 3.2 Davis, J.; Patil, J.; Aydin, N.; Mishra, A.; Misra, S. (2016). "Capsular nevus versus metastatic malignant melanoma - a diagnostic dilemma.". Int J Surg Case Rep 29: 20-24. doi:10.1016/j.ijscr.2016.10.040. PMID 27810606.