Difference between revisions of "AE1/AE3"
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{{ Infobox immunostain | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Abbrev = | |||
| Synonyms = | |||
| Similar = [[Z622]] | |||
| Clones = | |||
| Use = [[unknown primary]] | |||
| Subspecial = | |||
| Pattern = membranous | |||
| Positive = most carcinomas | |||
| Negative = most lymphomas, most sarcomas | |||
| Other = | |||
}} | |||
'''AE1/AE3''' is a common [[immunostain]] that marks keratins. It is considered a [[pankeratin]] by most. | '''AE1/AE3''' is a common [[immunostain]] that marks keratins. It is considered a [[pankeratin]] by most. | ||
Revision as of 20:49, 4 January 2019
| AE1/AE3 | |
|---|---|
| Immunostain in short | |
| Similar stains | Z622 |
| Use | unknown primary |
| Normal staining pattern | membranous |
| Positive | most carcinomas |
| Negative | most lymphomas, most sarcomas |
AE1/AE3 is a common immunostain that marks keratins. It is considered a pankeratin by most.
Positive
- Most or all carcinomas.
Sarcomas:
- Chordoma.
- Desmoplastic small round cell tumour.
- Most epithelioid sarcomas.
- Others.
Negative
- Most lymphomas.
- Most sarcomas.
See also
- CK7.
- CK20.
- EMA.
- Cytokeratin Z622.