Difference between revisions of "Adenoid cystic carcinoma of the breast"
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==Microscopic== | ==Microscopic== | ||
:See: ''[[Adenoid cystic carcinoma]]'' article. | :See: ''[[Adenoid cystic carcinoma]]'' article. | ||
DDx: | DDx: | ||
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*[[Collagenous spherulosis]]. | *[[Collagenous spherulosis]]. | ||
==Images== | ===Images=== | ||
<gallery> | <gallery> | ||
Image:Breast AdenoidCysticCarcinoma 2 LP CTR.jpg|Breast Adenoid Cystic Carcinoma - low power (SKB) | Image:Breast AdenoidCysticCarcinoma 2 LP CTR.jpg|Breast Adenoid Cystic Carcinoma - low power (SKB) | ||
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Image:Breast AdenoidCysticCarcinoma SolidType 2 14BR***.jpg|Breast Adenoid Cystic Carcinoma - Solid Type - high power (SKB) | Image:Breast AdenoidCysticCarcinoma SolidType 2 14BR***.jpg|Breast Adenoid Cystic Carcinoma - Solid Type - high power (SKB) | ||
</gallery> | </gallery> | ||
www: | |||
*[http://path.upmc.edu/cases/case140.html Adenoid cystic carcinoma of the breast (upmc.edu)]. | |||
==IHC== | |||
*One of the 'good prognosis' triple negative breast cancers - ER, PR and HER2 negative.<ref name=pmid16258515>{{Cite journal | last1 = Azoulay | first1 = S. | last2 = Laé | first2 = M. | last3 = Fréneaux | first3 = P. | last4 = Merle | first4 = S. | last5 = Al Ghuzlan | first5 = A. | last6 = Chnecker | first6 = C. | last7 = Rosty | first7 = C. | last8 = Klijanienko | first8 = J. | last9 = Sigal-Zafrani | first9 = B. | title = KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. | journal = Mod Pathol | volume = 18 | issue = 12 | pages = 1623-31 | month = Dec | year = 2005 | doi = 10.1038/modpathol.3800483 | PMID = 16258515 }}</ref> | |||
*Basal-like breast cancer - p63 and CK5/6 positive.<ref name=pmid16258515>{{Cite journal | last1 = Azoulay | first1 = S. | last2 = Laé | first2 = M. | last3 = Fréneaux | first3 = P. | last4 = Merle | first4 = S. | last5 = Al Ghuzlan | first5 = A. | last6 = Chnecker | first6 = C. | last7 = Rosty | first7 = C. | last8 = Klijanienko | first8 = J. | last9 = Sigal-Zafrani | first9 = B. | title = KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. | journal = Mod Pathol | volume = 18 | issue = 12 | pages = 1623-31 | month = Dec | year = 2005 | doi = 10.1038/modpathol.3800483 | PMID = 16258515 }}</ref> | |||
CD117 positive<ref name=pmid16258515>{{Cite journal | last1 = Azoulay | first1 = S. | last2 = Laé | first2 = M. | last3 = Fréneaux | first3 = P. | last4 = Merle | first4 = S. | last5 = Al Ghuzlan | first5 = A. | last6 = Chnecker | first6 = C. | last7 = Rosty | first7 = C. | last8 = Klijanienko | first8 = J. | last9 = Sigal-Zafrani | first9 = B. | title = KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. | journal = Mod Pathol | volume = 18 | issue = 12 | pages = 1623-31 | month = Dec | year = 2005 | doi = 10.1038/modpathol.3800483 | PMID = 16258515 }}</ref> | |||
==Other Resources== | ==Other Resources== | ||
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[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category: | [[Category:Invasive breast cancer]] | ||
Revision as of 08:00, 14 April 2015
Adenoid cystic carcinoma of the breast is a rare type of breast cancer that is similar to a relatively common tumour of the salivary gland.
General
- Like tumour of the salivary gland.
- Very rare <0.1% of breast malignancies.[1]
- Good prognosis.[1]
Microscopic
- See: Adenoid cystic carcinoma article.
DDx:
- Cribriform DCIS.
- Invasive cribriform carcinoma.
- Collagenous spherulosis.
Images
Breast Adenoid Cystic Carcinoma - low power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - medium power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast Adenoid Cystic Carcinoma - high power (SKB)
Breast - Adenoid Cystic Carcinoma - Solid Type - Low power (SKB)
Breast - Adenoid Cystic Carcinoma - Solid Type - medium power - Aggregates of basaloid cells without tubule or cyst formation. (SKB)
Breast - Adenoid Cystic Carcinoma - Solid Type - High power (SKB)
Breast Adenoid Cystic Carcinoma - Solid Type - high power (SKB)
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www:
IHC
- One of the 'good prognosis' triple negative breast cancers - ER, PR and HER2 negative.[2]
- Basal-like breast cancer - p63 and CK5/6 positive.[2]
CD117 positive[2]
Other Resources
Pathology Outlines [1]
See also
References
- ↑ 1.0 1.1 Boujelbene, N.; Khabir, A.; Boujelbene, N.; Jeanneret Sozzi, W.; Mirimanoff, RO.; Khanfir, K. (Dec 2011). "Clinical review - Breast adenoid cystic carcinoma.". Breast. doi:10.1016/j.breast.2011.11.006. PMID 22154460.
- ↑ 2.0 2.1 2.2 Azoulay, S.; Laé, M.; Fréneaux, P.; Merle, S.; Al Ghuzlan, A.; Chnecker, C.; Rosty, C.; Klijanienko, J. et al. (Dec 2005). "KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome.". Mod Pathol 18 (12): 1623-31. doi:10.1038/modpathol.3800483. PMID 16258515.