Difference between revisions of "Male infertility"
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| Line 27: | Line 27: | ||
*Inflammation. | *Inflammation. | ||
*Absence of [[intratubular germ cell neoplasia]]. | *Absence of [[intratubular germ cell neoplasia]]. | ||
===Mixed pattern=== | |||
<pre> | |||
LEFT TESTIS, BIOPSY FOR SPERM RETRIEVAL: | |||
- SERTOLI CELLS ONLY REGIONS (25% OF BIOPSY) INTERMEIXED WITH | |||
HISTOLOGICALLY NORMAL TESTIS (75% OF BIOPSY) WITH NORMAL NUMBERS | |||
OF SPERM. | |||
- NEGATIVE FOR SIGNIFICANT SEMINIFEROUS TUBULE HYALINIZATION. | |||
- NEGATIVE FOR SIGNIFICANT INFLAMMATION. | |||
- NEGATIVE FOR INTRATUBULAR GERM CELL NEOPLASIA. | |||
</pre> | |||
==See also== | ==See also== | ||
Revision as of 16:41, 9 March 2015
Male infertility is a clinical diagnosis. It is pretty much the only reason for a testicular biopsy.
General
- Infertility is a clinical diagnosis.
It can be divided into:[1]
- Pre-testicular - e.g. hormonal, pituitary.
- Testicular.
- Post-testicular - e.g. blockage of vas deferens.
Microscopic
Male infertility on testicular biopsy shows one the following patterns:[1]
- Normal testis.
- Hypospermatogensis.
- Maturation arrest.
- Sertoli cells only.
- Seminiferous tubule hyalinization
- A combination of the above.
Sign out
- The diagnosis should be the pattern (#1-6 above).
The following should be commented on:
- The number of tubules.
- The number of tubules with sperm.
- Hyalinization of the tubules.
- Inflammation.
- Absence of intratubular germ cell neoplasia.
Mixed pattern
LEFT TESTIS, BIOPSY FOR SPERM RETRIEVAL: - SERTOLI CELLS ONLY REGIONS (25% OF BIOPSY) INTERMEIXED WITH HISTOLOGICALLY NORMAL TESTIS (75% OF BIOPSY) WITH NORMAL NUMBERS OF SPERM. - NEGATIVE FOR SIGNIFICANT SEMINIFEROUS TUBULE HYALINIZATION. - NEGATIVE FOR SIGNIFICANT INFLAMMATION. - NEGATIVE FOR INTRATUBULAR GERM CELL NEOPLASIA.