Difference between revisions of "Smooth muscle tumour of uncertain malignant potential"

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*p16 +ve.
*p16 +ve.
*p53 +ve.
*p53 +ve.


==See also==
==See also==

Revision as of 02:35, 23 October 2014

Smooth muscle tumour of uncertain malignant potential, abbreviated STUMP is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.

General

  • Like ASAP and ASCUS - a waffle category... when one isn't sure it is a leiomyoma vs. leiomyosarcoma.
  • Clinical behaviour in uterus: usually benign.[1]
  • Can be subclassified into four groups - as per Stanford.
  • May be seen in the prostate gland.[2]

Management:

  • Long-term follow-up.[1]

Microscopic

Features associated with recurrence:[1]

  • Nuclear atypia.

DDx:

IHC

Features associated with recurrence:[1]

  • p16 +ve.
  • p53 +ve.

See also

References

  1. 1.0 1.1 1.2 1.3 Ip PP, Cheung AN, Clement PB (July 2009). "Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases". Am. J. Surg. Pathol. 33 (7): 992–1005. doi:10.1097/PAS.0b013e3181a02d1c. PMID 19417585.
  2. Nagar, M.; Epstein, JI. (Jun 2011). "Epithelial proliferations in prostatic stromal tumors of uncertain malignant potential (STUMP).". Am J Surg Pathol 35 (6): 898-903. doi:10.1097/PAS.0b013e318214f2f2. PMID 21572264.