Difference between revisions of "Crystals in body fluids"
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**''Diamonds'' are see-through; ergo, uric acid stones not seen on KUB. | **''Diamonds'' are see-through; ergo, uric acid stones not seen on KUB. | ||
**Calcium oxalat'''e''' = '''e'''nvelope, uric aci'''d''' = '''d'''iamond. | **Calcium oxalat'''e''' = '''e'''nvelope, uric aci'''d''' = '''d'''iamond. | ||
*Uric acid crystals: usually dissolve in [[formalin]]... but do not dissolve in alcohol.<ref>Geddie, W. 8 January 2010.</ref> | *Uric acid crystals: usually dissolve in [[formalin]]... but do not dissolve in alcohol.<ref>Geddie, W. 8 January 2010.</ref><ref>{{Cite journal | last1 = Shidham | first1 = V. | last2 = Chivukula | first2 = M. | last3 = Basir | first3 = Z. | last4 = Shidham | first4 = G. | title = Evaluation of crystals in formalin-fixed, paraffin-embedded tissue sections for the differential diagnosis of pseudogout, gout, and tumoral calcinosis. | journal = Mod Pathol | volume = 14 | issue = 8 | pages = 806-10 | month = Aug | year = 2001 | doi = 10.1038/modpathol.3880394 | PMID = 11504841 }}</ref> | ||
*Calcium oxalate crystals are seen in the context of [[ethylene glycol]] poisoning.<ref name=Ref_KFP589>{{Ref KFP|589}}</ref> | *Calcium oxalate crystals are seen in the context of [[ethylene glycol]] poisoning.<ref name=Ref_KFP589>{{Ref KFP|589}}</ref> | ||
Revision as of 02:09, 19 October 2014
This article deals with crystals in body fluids.
Crystals
Joint crystals
Types:[1]
- Gout = needle-shaped, negatively birefringent, yellow when aligned.
- Pseudogout = rhomboid-shaped, positively birefringent, blue when aligned.
Notes:
- Pseudogout also known as CPPD = calcium pyrophosphate dehydrogenase.
- Memory device: ABC+ = aligned blue is calcium & cuboid - positively birefringent.
Urine crystals
Types - morphology:
- Envelope shape (calcium oxalate).
- Diamond shape (uric acid).
- Coffin-lid shape (struvite).
- Hexagonal shape (cysteine).
Notes:
- Memory devices:
- Diamonds are see-through; ergo, uric acid stones not seen on KUB.
- Calcium oxalate = envelope, uric acid = diamond.
- Uric acid crystals: usually dissolve in formalin... but do not dissolve in alcohol.[2][3]
- Calcium oxalate crystals are seen in the context of ethylene glycol poisoning.[4]
Diseases
Gout
Main article: Gout
Pseudogout
Main article: Chondrocalcinosis
See also
- Cytopathology.
- Medical renal diseases.
- Nephrolithiasis - kidney stones.
References
- ↑ Yeung, J.C.; Leonard, Blair J. N. (2005). The Toronto Notes 2005 - Review for the MCCQE and Comprehensive Medical Reference (2005 ed.). The Toronto Notes Inc. for Medical Students Inc.. pp. RH6. ISBN 978-0968592854.
- ↑ Geddie, W. 8 January 2010.
- ↑ Shidham, V.; Chivukula, M.; Basir, Z.; Shidham, G. (Aug 2001). "Evaluation of crystals in formalin-fixed, paraffin-embedded tissue sections for the differential diagnosis of pseudogout, gout, and tumoral calcinosis.". Mod Pathol 14 (8): 806-10. doi:10.1038/modpathol.3880394. PMID 11504841.
- ↑ Saukko, Pekka; Knight, Bernard (2004). Knight's Forensic Pathology (3rd ed.). A Hodder Arnold Publication. pp. 589. ISBN 978-0340760444.
- ↑ URL: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001458/. Accessed on: 28 October 2011.