Difference between revisions of "Adenomatoid tumour"
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'''Adenomatoid tumour''' is a rare benign tumour derived from the [[mesothelium]]. | |||
It should '''not''' be confused with the [[bone tumour]] ''[[adamantinoma]]''. | |||
==General== | |||
*Grossly mimics leiomyoma.<ref name=pmid8543111>{{Cite journal | last1 = Huang | first1 = CC. | last2 = Chang | first2 = DY. | last3 = Chen | first3 = CK. | last4 = Chou | first4 = YY. | last5 = Huang | first5 = SC. | title = Adenomatoid tumor of the female genital tract. | journal = Int J Gynaecol Obstet | volume = 50 | issue = 3 | pages = 275-80 | month = Sep | year = 1995 | doi = | PMID = 8543111 }} | |||
</ref> | |||
*Benign tumour - derived from mesothelium. | |||
*May be seen paratesticular.<ref name=pmid20223139>{{Cite journal | last1 = González Resina | first1 = R. | last2 = Carranza Carranza | first2 = A. | last3 = Congregado Córdoba | first3 = J. | last4 = Conde Sánchez | first4 = JM. | last5 = Congregado Ruiz | first5 = CB. | last6 = Medina López | first6 = R. | title = [Paratesticular adenomatoid tumor: a report of nine cases]. | journal = Actas Urol Esp | volume = 34 | issue = 1 | pages = 95-100 | month = Jan | year = 2010 | doi = | PMID = 20223139 }} | |||
</ref> | |||
==Microscopic== | |||
Features:<ref>{{Ref GP|346}}</ref> | |||
*Well-circumscribed lesion; however, ''not'' encapsulated. | |||
*Small tubulocystic spaces lined by cytologically normal mesothelium. | |||
**These pseudotubular spaces are crossed by "thread-like bridging strands" - '''key feature'''.<ref name=pmid19543245>{{Cite journal | last1 = Sangoi | first1 = AR. | last2 = McKenney | first2 = JK. | last3 = Schwartz | first3 = EJ. | last4 = Rouse | first4 = RV. | last5 = Longacre | first5 = TA. | title = Adenomatoid tumors of the female and male genital tracts: a clinicopathological and immunohistochemical study of 44 cases. | journal = Mod Pathol | volume = 22 | issue = 9 | pages = 1228-35 | month = Sep | year = 2009 | doi = 10.1038/modpathol.2009.90 | PMID = 19543245 }}</ref><ref name=pmid14571427>{{Cite journal | last1 = Hes | first1 = O. | last2 = Perez-Montiel | first2 = DM. | last3 = Alvarado Cabrero | first3 = I. | last4 = Zamecnik | first4 = M. | last5 = Podhola | first5 = M. | last6 = Sulc | first6 = M. | last7 = Hora | first7 = M. | last8 = Mukensnabl | first8 = P. | last9 = Zalud | first9 = R. | title = Thread-like bridging strands: a morphologic feature present in all adenomatoid tumors. | journal = Ann Diagn Pathol | volume = 7 | issue = 5 | pages = 273-7 | month = Oct | year = 2003 | doi = | PMID = 14571427 }}</ref> | |||
DDx: | |||
*[[Lymphangioma]]. | |||
*[[Leiomyoma]]. | |||
===Images=== | |||
<gallery> | |||
Image:Adenomatoid_tumour_-_low_mag.jpg | Adenomatoid tumour - low mag. (WC) | |||
Image:Adenomatoid_tumour_-_intermed_mag.jpg | Adenomatoid tumour - intermed. mag. (WC) | |||
Image:Adenomatoid_tumour_-_high_mag.jpg | Adenomatoid tumour - high mag. (WC) | |||
Image:Adenomatoid_tumour_-b-_very_high_mag.jpg | Adenomatoid tumour - very high mag. (WC) | |||
</gallery> | |||
==IHC== | |||
Features:<ref name=pmid16548294>{{Cite journal | last1 = Canedo-Patzi | first1 = AM. | last2 = León-Bojorge | first2 = B. | last3 = de Ortíz-Hidalgo | first3 = C. | title = [Adenomatoid tumor of the genital tract. Clinical, pathological and immunohistochemical study in 9 cases] | journal = Gac Med Mex | volume = 142 | issue = 1 | pages = 59-66 | month = | year = | doi = | PMID = 16548294 }} | |||
</ref> | |||
*Calretinin +ve. | |||
*AE1/AE3 +ve. | |||
*CD31 -ve. | |||
*CK7 +ve.<ref>Latta, E. 9 December 2009.</ref> | |||
==See also== | |||
*[[Uterine tumours]]. | |||
*[[Fallopian tube]]. | |||
*[[Benign multicystic mesothelioma]]. | |||
*[[Malignant mesothelioma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Gynecologic pathology]] | |||
Revision as of 02:26, 22 November 2013
Adenomatoid tumour is a rare benign tumour derived from the mesothelium.
It should not be confused with the bone tumour adamantinoma.
General
- Grossly mimics leiomyoma.[1]
- Benign tumour - derived from mesothelium.
- May be seen paratesticular.[2]
Microscopic
Features:[3]
- Well-circumscribed lesion; however, not encapsulated.
- Small tubulocystic spaces lined by cytologically normal mesothelium.
DDx:
Images
Adenomatoid tumour - low mag. (WC)
Adenomatoid tumour - intermed. mag. (WC)
Adenomatoid tumour - high mag. (WC)
Adenomatoid tumour - very high mag. (WC)
IHC
Features:[6]
- Calretinin +ve.
- AE1/AE3 +ve.
- CD31 -ve.
- CK7 +ve.[7]
See also
References
- ↑ Huang, CC.; Chang, DY.; Chen, CK.; Chou, YY.; Huang, SC. (Sep 1995). "Adenomatoid tumor of the female genital tract.". Int J Gynaecol Obstet 50 (3): 275-80. PMID 8543111.
- ↑ González Resina, R.; Carranza Carranza, A.; Congregado Córdoba, J.; Conde Sánchez, JM.; Congregado Ruiz, CB.; Medina López, R. (Jan 2010). "[Paratesticular adenomatoid tumor: a report of nine cases].". Actas Urol Esp 34 (1): 95-100. PMID 20223139.
- ↑ Nucci, Marisa R.; Oliva, Esther (2009). Gynecologic Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 346. ISBN 978-0443069208.
- ↑ Sangoi, AR.; McKenney, JK.; Schwartz, EJ.; Rouse, RV.; Longacre, TA. (Sep 2009). "Adenomatoid tumors of the female and male genital tracts: a clinicopathological and immunohistochemical study of 44 cases.". Mod Pathol 22 (9): 1228-35. doi:10.1038/modpathol.2009.90. PMID 19543245.
- ↑ Hes, O.; Perez-Montiel, DM.; Alvarado Cabrero, I.; Zamecnik, M.; Podhola, M.; Sulc, M.; Hora, M.; Mukensnabl, P. et al. (Oct 2003). "Thread-like bridging strands: a morphologic feature present in all adenomatoid tumors.". Ann Diagn Pathol 7 (5): 273-7. PMID 14571427.
- ↑ Canedo-Patzi, AM.; León-Bojorge, B.; de Ortíz-Hidalgo, C.. "[Adenomatoid tumor of the genital tract. Clinical, pathological and immunohistochemical study in 9 cases]". Gac Med Mex 142 (1): 59-66. PMID 16548294.
- ↑ Latta, E. 9 December 2009.