Difference between revisions of "Hibernoma"
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'''Hibernoma''' is an uncommon tumour of brown fat. It is an [[adipocytic tumours|adipocytic tumour]]. | |||
==General== | |||
*Consists of ''brown fat'' (present in the infants to generate heat).<ref name=Ref_WMSP605>{{Ref WMSP|605}}</ref> | |||
*Benign. | |||
*Usually asymptomatic.<ref name=pmid19131775>{{cite journal |author=Ahmed SA, Schuller I |title=Pediatric hibernoma: a case review |journal=J. Pediatr. Hematol. Oncol. |volume=30 |issue=12 |pages=900–1 |year=2008 |month=December |pmid=19131775 |doi=10.1097/MPH.0b013e318184e6dd |url=}}</ref> | |||
Epidemiology: | |||
*Young adults. | |||
==Gross== | |||
*Well-circumscribed. | |||
*Lobulated and light-brown on sectioning. | |||
==Microscopic== | |||
Features:<ref name=pmid9537018>{{cite journal |author=Chen DY, Wang CM, Chan HL |title=Hibernoma. Case report and literature review |journal=Dermatol Surg |volume=24 |issue=3 |pages=393–5 |year=1998 |month=March |pmid=9537018 |doi= |url=}}</ref> | |||
*Large polygonal/oval cells: | |||
**Nucleus - central & small.<ref>[http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70271-6 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70271-6]</ref> | |||
***Nucleoli typically prominent.<ref>[http://surgpathcriteria.stanford.edu/softfat/hibernoma/ http://surgpathcriteria.stanford.edu/softfat/hibernoma/]</ref> | |||
**Cytoplasm - multivacuolated, oval, eosinophilic, granular. | |||
*+/-Prominent blood vessels, central.<ref>URL: [http://radiographics.rsna.org/content/24/5/1433.full http://radiographics.rsna.org/content/24/5/1433.full]. Accessed on: 11 February 2013.</ref> | |||
DDx: | |||
*Reaction to silicone implant. | |||
===Image=== | |||
<gallery> | |||
Image:Hibernoma1.jpg | Hibernoma - high mag. (WC) | |||
Image:Hibernoma3.jpg | Hibernoma - intermed mag. (WC) | |||
Image:Hibernoma3.jpg | Hibernoma - low mag. (WC) | |||
</gallery> | |||
==See also== | |||
*[[Adipocytic tumours]]. | |||
*[[Lipoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Adipocytic tumours]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Revision as of 13:34, 28 September 2013
Hibernoma is an uncommon tumour of brown fat. It is an adipocytic tumour.
General
- Consists of brown fat (present in the infants to generate heat).[1]
- Benign.
- Usually asymptomatic.[2]
Epidemiology:
- Young adults.
Gross
- Well-circumscribed.
- Lobulated and light-brown on sectioning.
Microscopic
Features:[3]
- Large polygonal/oval cells:
- +/-Prominent blood vessels, central.[6]
DDx:
- Reaction to silicone implant.
Image
Hibernoma - high mag. (WC)
Hibernoma - intermed mag. (WC)
Hibernoma - low mag. (WC)
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 605. ISBN 978-0781765275.
- ↑ Ahmed SA, Schuller I (December 2008). "Pediatric hibernoma: a case review". J. Pediatr. Hematol. Oncol. 30 (12): 900–1. doi:10.1097/MPH.0b013e318184e6dd. PMID 19131775.
- ↑ Chen DY, Wang CM, Chan HL (March 1998). "Hibernoma. Case report and literature review". Dermatol Surg 24 (3): 393–5. PMID 9537018.
- ↑ http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70271-6
- ↑ http://surgpathcriteria.stanford.edu/softfat/hibernoma/
- ↑ URL: http://radiographics.rsna.org/content/24/5/1433.full. Accessed on: 11 February 2013.