Talk:Ditzels

Hernia sac - generic

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Microscopic description

The section shows benign fibrofatty/fibrous tissue with a mesothelial lining.

Final diagnosis

Hernia sac, left/right, excision - hernia sac (left/right inguinal).

Hernia sac

Microscopic description

The section shows benign fibrous tissue with a mesothelial lining.

Final diagnosis

Hernia sac, left, excision - hernia sac (left inguinal).

Adhesive band (band of Ladd)

Microscopic description

The section shows benign vascular fibrous tissue.

Final diagnosis

Adhesive band, Ladd's procedure - vascular fibrous tissue consistent with bands of Ladd.

Granulation tissue

Microscopic description

The section shows edematous, well-vascularized fibrous tissue with abundant plasma cells and abundant neutrophils. At the center of the lesion are hemosiderin-laden macrophages and at the periphery multi-nucleated giant cells. No foreign material was identified with polarization.

Final diagnosis

Granuloma, left ear, excision - inflammed granulation tissue.

Keratinaceous debris (cholesteatoma)

Microscopic description

The section shows keratinaceous debris. There are no viable cells.

Final diagnosis

Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris.

Cholesteatoma 1

Microscopic description

The section shows lamellar keratin, abundant reactive histiocytes and multinucleated giant cells. Lymphocytes and plasma cells are present. There is dystrophic calcification. Fragments of bone are seen.

Final diagnosis

Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris and inflammation (consistent with cholesteatoma).

Cholesteatoma 2

Microscopic description

The section shows lamellar keratin, a fragment of squamous epithelium and fragments of bone. No significant inflammation is identified.

Final diagnosis

Soft tissue, left ear ("left ear keratosis"), excision - keratinaceous debris, squamous epithelium and bone (consistent with cholesteatoma).

Stoma

Microscopic description

The sections show mature squamous epithelium with parakeratosis, and colonic-type mucosa with focal lymphoid hyperplasia and reactive epithelial changes. The colonic-type mucosa has focal paneth cells, crypt dilation, mild crypt distortion and fibromuscular hyperplasia of the lamina propria and submucsoa. Foreign body-type granulomas (suture granulomas) are present in the lamina propria. Normal bowel wall smooth muscle is present. Ganglion cells are present.

Final diagnosis

A. Sigmoid, excision - benign squamous epithelium and intestine wall with reactive colonic-type epithelium (consistent with stoma).

Foreskin

FORESKIN, EXCISION:
- STRATIFIED SQUAMOUS EPITHELIUM WITH KERATINIZATION, MILD FOCAL LYMPHOCYTIC INFILTRATE AND FOCAL ULCERATION.
- FIBROUS DERMAL TISSUE WITH PERIVASCULAR LYMPHOPLASMACYTIC INFILTRATE.
- NEGATIVE FOR MALIGNANCY.

Nail plate

PARTIAL NAIL PLATE, RIGHT THIRD TOE, SCISSOR EXCISION:
- NAIL PLATE AND THIN LAYER OF KERATINIZED SQUAMOUS EPITHELIUM WITH
  PARAKERATOSIS AND FIBRIN.
- NO APPARENT PIGMENT.
- NO EVIDENCE OF MALIGNANCY.

Micro

The sections show a paucicellular nail plate, and a thin layer of squamous epithelium with keratinization and partial retention of the nuclei (parakeratosis). There is also a small amount of fibrin. No pigmentation is apparent with Prussian blue and Fontana-Masson staining. No melanocytes are apparent. No nuclear atypia is apparent. No mitotic activity is identified. No microorganisms are apparent. No significant inflammation is apparent.

Another nail

GREAT TOENAIL, RIGHT, EXCISION:
- NAIL PLATE AND THIN LAYER OF KERATINIZED SQUAMOUS EPITHELIUM.
- SMALL CLUSTERS OF COCCI, FOCAL.
- NO APPARENT FUNGAL ORGANISMS WITH PASF STAIN.
- NO EVIDENCE OF MALIGNANCY.

Floppy eyelid syndrome

RIGHT EYE, SUPERIOR TARSAL CONJUNCTIVA, BIOPSY:
- COMPATIBLE WITH CONJUNCTIVAL MUCOSA WITH FOCAL PARAKERATOSIS AND HYPERGRANULOSIS,
  RARE INTRAEPITHELIAL LYMPHOCYTES, DILATED SUPERFICIAL BLOOD VESSELS, AND A MILD
  PERIVASCULAR LYMPHOPLASMACYTIC INFILTRATE.
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.