Difference between revisions of "Myopericytoma"
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==General== | ==General== | ||
* | *Usually benign. | ||
*Typically in the distal extremities.<ref name=pmid21111282>{{cite journal |author=Zidane A, Arsalane A, Harkat A, ''et al.'' |title=[Myopericytoma: an uncommon chest wall tumor] |language=French |journal=Rev Mal Respir |volume=27 |issue=9 |pages=1089–91 |year=2010 |month=November |pmid=21111282 |doi=10.1016/j.rmr.2010.09.017 |url=}}</ref> | *Typically in the distal extremities.<ref name=pmid21111282>{{cite journal |author=Zidane A, Arsalane A, Harkat A, ''et al.'' |title=[Myopericytoma: an uncommon chest wall tumor] |language=French |journal=Rev Mal Respir |volume=27 |issue=9 |pages=1089–91 |year=2010 |month=November |pmid=21111282 |doi=10.1016/j.rmr.2010.09.017 |url=}}</ref> | ||
*Used to be classified as ''[[hemangiopericytoma]]'' (AKA solitary fibrous tumour). | *Used to be classified as ''[[hemangiopericytoma]]'' (AKA solitary fibrous tumour). | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref>{{cite journal |author=Edgecombe A, Peterson RA, Shamji FM, Commons S, Sekhon H, Gomes MM |title=Myopericytoma: a pleural-based spindle cell neoplasm off the beaten path |journal=Int. J. Surg. Pathol. |volume=19 |issue=2 |pages=247–51 |year=2011 |month=April |pmid=21474507 |doi=10.1177/1066896910381897 |url=}}</ref><ref name=Ref_WMSP615>{{Ref WMSP|615}}</ref> | Features:<ref name=pmid21474507>{{cite journal |author=Edgecombe A, Peterson RA, Shamji FM, Commons S, Sekhon H, Gomes MM |title=Myopericytoma: a pleural-based spindle cell neoplasm off the beaten path |journal=Int. J. Surg. Pathol. |volume=19 |issue=2 |pages=247–51 |year=2011 |month=April |pmid=21474507 |doi=10.1177/1066896910381897 |url=}}</ref><ref name=Ref_WMSP615>{{Ref WMSP|615}}</ref> | ||
*Fasicular pattern - may be subtle - with: | *Fasicular pattern - may be subtle - with: | ||
**Compressed blood vessels, often thin walled & branching. | **Compressed blood vessels, often thin walled & branching. | ||
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DDx: | DDx: | ||
*[[Solitary fibrous tumour]]. | *[[Solitary fibrous tumour]]. | ||
* | *[[Vascular tumours]]. | ||
Images: | Images: | ||
Revision as of 00:04, 26 April 2012
Myopericytoma, also glomangiopericytoma, is a rare perivascular soft tissue tumour.
General
- Usually benign.
- Typically in the distal extremities.[1]
- Used to be classified as hemangiopericytoma (AKA solitary fibrous tumour).
Microscopic
- Fasicular pattern - may be subtle - with:
- Compressed blood vessels, often thin walled & branching.
- Increased peri-vascular cellularity.
- Cellular lesion:
- Small bland unequally spaced epithelioid/spindle cells.
- Moderate eosinophilic cytoplasm.
Notes:
- Features overlap with myofibroma.[4]
DDx:
Images:
IHC
- SMA +ve.
- H-caldesmon +ve.
- CD34 +ve (focal).
Others:[5]
- AE1/AE3 -ve.
- EMA -ve.
See also
- Glomus tumour - the other perivascular tumour.
- Soft tissue lesions.
References
- ↑ Zidane A, Arsalane A, Harkat A, et al. (November 2010). "[Myopericytoma: an uncommon chest wall tumor]" (in French). Rev Mal Respir 27 (9): 1089–91. doi:10.1016/j.rmr.2010.09.017. PMID 21111282.
- ↑ Edgecombe A, Peterson RA, Shamji FM, Commons S, Sekhon H, Gomes MM (April 2011). "Myopericytoma: a pleural-based spindle cell neoplasm off the beaten path". Int. J. Surg. Pathol. 19 (2): 247–51. doi:10.1177/1066896910381897. PMID 21474507.
- ↑ 3.0 3.1 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 615. ISBN 978-0781765275.
- ↑ Dray MS, McCarthy SW, Palmer AA, et al. (January 2006). "Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases". J. Clin. Pathol. 59 (1): 67–73. doi:10.1136/jcp.2005.028704. PMC 1860256. PMID 16394283. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860256/.
- ↑ 5.0 5.1 URL: http://e-immunohistochemistry.info/web/Myopericytoma.htm. Accessed on: 6 May 2011.