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Difference between revisions of "Prostate gland"
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→Mimics: tweak
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| fern-like arrangement of epithelium (low power), nucleoli, surrounded by muscle, +/- nuclear inclusions | | fern-like arrangement of epithelium (low power), nucleoli, surrounded by muscle, +/- nuclear inclusions | ||
| involvement by cancer changes staging, lipofuscin may be present in prostate, often has marked nuc. size var. | | involvement by cancer changes staging, lipofuscin may be present in prostate, often has marked nuc. size var. | ||
| [http://commons.wikimedia.org/wiki/File:Seminal_vesicle_high_mag.jpg SV - high mag.], [http://commons.wikimedia.org/wiki/File:Seminal_vesicle_low_mag.jpg SV - low mag.] | | [http://commons.wikimedia.org/wiki/File:Seminal_vesicle_high_mag.jpg SV - high mag. (WC)], [http://commons.wikimedia.org/wiki/File:Seminal_vesicle_low_mag.jpg SV - low mag. (WC)] | ||
|- | |- | ||
| Radiation | | Radiation effect | ||
| marked nuclear size variation | | marked nuclear size variation | ||
| increased stroma (fibrosis), lack nucleoli ??? | | increased stroma (fibrosis), lack nucleoli ??? | ||
| Line 385: | Line 385: | ||
| no nuclear atypia, normal gland arch. | | no nuclear atypia, normal gland arch. | ||
| clinical mimic of cancer (elevated PSA); usu. not a problem for the pathologist | | clinical mimic of cancer (elevated PSA); usu. not a problem for the pathologist | ||
| [http://commons.wikimedia.org/wiki/File:Inflammation_of_prostate.jpg] | | [http://commons.wikimedia.org/wiki/File:Inflammation_of_prostate.jpg (WC)] | ||
|- | |||
| [[Vasitis nodosa]] | |||
| sperm within ducts, clinical history (usu. post-vasectomy) | |||
| small tubules, nucleoli common, mild atypia, may "invade" vessels, track along nerves | |||
| mimics metastatic prostate carcinoma, IHC stains: PSA-, PSAP- | |||
| [http://www.webpathology.com/image.asp?n=11&Case=40 VN (webpathology.com)] | |||
|} | |} | ||
Memory device: '''AAABBRS''' = | Memory device: '''AAABBRS''' = atrophy, adenosis, adenosis (sclerosing), basal cell hyperplasia, bulbourethral gland, radiation, seminal vesicles. | ||
===Grading=== | ===Grading=== | ||