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Ditzels (view source)

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→‎Tenosynovitis
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==Tenosynovitis==
==Tenosynovitis==
:''Stenosing tenosynovitis'' directs here.
{{Main|Tenosynovitis}}
===General===
*Uncommon pathology specimen.
*May cause ''trigger finger''.<ref name=pmid23396894>{{Cite journal  | last1 = Vuillemin | first1 = V. | last2 = Guerini | first2 = H. | last3 = Bard | first3 = H. | last4 = Morvan | first4 = G. | title = Stenosing tenosynovitis. | journal = J Ultrasound | volume = 15 | issue = 1 | pages = 20-8 | month = Feb | year = 2012 | doi = 10.1016/j.jus.2012.02.002 | PMID = 23396894 }}</ref>
 
===Microscopic===
Features:<ref name=pmid20442645>{{Cite journal  | last1 = Shon | first1 = W. | last2 = Folpe | first2 = AL. | title = Tenosynovitis with psammomatous calcification: a poorly recognized pseudotumor related to repetitive tendinous injury. | journal = Am J Surg Pathol | volume = 34 | issue = 6 | pages = 892-5 | month = Jun | year = 2010 | doi = 10.1097/PAS.0b013e3181d95a36 | PMID = 20442645 }}</ref>
*Dense connective tissue (tendon).
*Histiocytes.
*+/-[[Psammoma bodies]].
 
DDx:
*Calcific tendinitis.
*[[Giant cell tumour of the tendon sheath]].
*[[Palmar fibromatosis]].
 
===IHC===
Features:
*CD68 +ve.
*Beta-catenin -ve.
 
Note:
*Immunostains are usually not required for the diagnosis.
 
===Sign out===
<pre>
Tenosynovium, Left Wrist, Excision:
- Dense connective tissue (consistent with tendon) with degenerative
  changes and lymphohistiocytic infiltrate
- NEGATIVE for apparent giant cells and NEGATIVE for calcification.
- NEGATIVE or malignancy.
</pre>
 
====Block letters====
<pre>
TENOSYNOVIUM, LEFT MIDDLE FINGER, EXCISION:
- DENSE CONNECTIVE TISSUE (CONSISTENT WITH TENDON) WITH LYMPHOHISTIOCYTIC INFILTRATE.
- NEGATIVE FOR GIANT CELLS.
- NEGATIVE FOR MALIGNANCY.
</pre>
 
====Micro====
The sections show dense connective tissue (tendon) containing a cluster of cells with
indistinct cellular borders, abundant foamy grey cytoplasm, and round/oval
pale-staining nuclei with small nucleoli (histiocytes).  The cell cluster has a small
number of interspersed lymphocytes, and the centre of the cell cluster has acellular
hyaline material (degenerative tendon).
 
No calcification is identified. No giant cells are seen.
 
No nuclear atypia is apparent and no mitotic activity is appreciated.
 
=====Alternate=====
The sections show dense connective tissue (tendon) containing rare histiocytes and
lymphocytes. No calcification is identified. No giant cells are seen.  No nuclear atypia
is apparent and no mitotic activity is appreciated.


==Otosclerosis==
==Otosclerosis==
Michael
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