Difference between revisions of "Esophagus"

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==Squamous cell carcinoma of the esophagus==
==Squamous cell carcinoma of the esophagus==
*[[AKA]] ''esophageal squamous cell carcinoma'', abbreviated ''esophageal SCC''.
*[[AKA]] ''esophageal squamous cell carcinoma'', abbreviated ''esophageal SCC''.
{{Main|Squamous carcinoma}}
{{Main|Squamous cell carcinoma of the esophagus}}
===General===
*Like squamous cell carcinoma elsewhere.
 
Risk factors:<ref name=Ref_APBR104>{{Ref APBR|104 Q1}}</ref>
*[[Ethanol abuse|Alcohol consumption]].
*[[Smoking|Tobacco use]].
*Food with nitrosamines.
*Burning-hot beverages.
 
Note:
*Reflux is ''not'' a risk factor for esophageal SCC.
 
===Microscopic===
:See ''[[Squamous carcinoma]]''.
 
Note:
*Just to make things confusing, the ''Staging'' of early SCC differs from that of early adenocarcinoma!
 
DDx:
*[[Squamous dysplasia of the esophagus]].
 
====Images====
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig08/ Carcinoma in situ (nih.gov)].<ref name=pmid23330004>{{Cite journal  | last1 = Terada | first1 = T. | title = A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 2 | pages = 191-8 | month =  | year = 2013 | doi =  | PMID = 23330004 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238/figure/fig09/ Squamous cell carcinoma of the esophagus (nih.gov)].
 
===Sign out===
<pre>
ESOPHGAUS, BIOPSY:
- INVASIVE SQUAMOUS CELL CARCINOMA, KERATINIZING, MODERATELY DIFFERENTIATED.
 
COMMENT:
Benign squamous epithelium at least partially overlies the invasive squamous
cell carcinoma; this may mask the true extent of the lesion on endoscopy.
</pre>
 
====Micro====
The sections show a squamous mucosa with focal moderate atypia of the squamous cells,
keratinization and easily identified mitotic figures. The atypical cells are partially
covered by benign squamous cells, and there is a very sharp transition between the cells
with atypia and those without. The atypical squamous cells extend into the subepithelial tissue in irregularly shaped nests and cords. A small amount of benign muscle is present.


==Esophageal adenocarcinoma==
==Esophageal adenocarcinoma==
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