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The columnar epithelium has focal involvement by the squamous lesion. There is no columnar dysplasia. The margins are negative for dysplasia. | The columnar epithelium has focal involvement by the squamous lesion. There is no columnar dysplasia. The margins are negative for dysplasia. | ||
=====Alternate===== | |||
The sections show fragments of transformation zone. | |||
There is dysplastic squamous epithelium with coarse chromatin, nuclear hyperchromasia, | |||
nuclear enlargement, irregular nuclear membranes, and an increase nuclear-to-cytoplasmic | |||
ratio. Mitotic activity is abundant focally (5 mitoses/0.2376 mm*mm). The dysplastic | |||
squamous epithelium does not show appreciable maturation toward the surface (CIN 3). | |||
The dysplastic squamous epithelium is not associated with stroma; thus, the | |||
presence/absence of invasion cannot be assessed. Small nucleoli are seen rarely. | |||
There is benign squamous epithelium. Scant benign stripped endocervical epithelium is | |||
present. | |||
==Endocervical adenocarcinoma in situ== | ==Endocervical adenocarcinoma in situ== |
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