Difference between revisions of "Breast pathology"

Jump to navigation Jump to search
Line 287: Line 287:
===Microscopic===
===Microscopic===
Features:
Features:
*Acini are smaller than usual and there are more of them.
*Acini are smaller than usual and there are more of them - often slit-like.
*Fibrosis (scleroses) - pink on H&E surrounds the acini.  
*Fibrosis (scleroses) - pink on H&E surrounds the acini.  
**Can mimic a [[dysmoplastic reaction]].
**Can mimic a [[dysmoplastic reaction]].
Line 294: Line 294:
*The acini should:
*The acini should:
**Be in lobular arrangements, i.e. in groups (benign appearance at low power).
**Be in lobular arrangements, i.e. in groups (benign appearance at low power).
**Round.
**Have two cell layers like well-behaved breast glands do - '''key feature'''.
**Have two cell layers like well-behaved breast glands do - '''key feature'''.