Difference between revisions of "Uterine cervix"
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===IHC=== | ===IHC=== | ||
Features:<ref name=pmid22162342>{{Cite journal | last1 = Singh | first1 = M. | last2 = Mockler | first2 = D. | last3 = Akalin | first3 = A. | last4 = Burke | first4 = S. | last5 = Shroyer | first5 = A. | last6 = Shroyer | first6 = KR. | title = Immunocytochemical colocalization of P16(INK4a) and Ki-67 predicts CIN2/3 and AIS/adenocarcinoma. | journal = Cancer Cytopathol | volume = 120 | issue = 1 | pages = 26-34 | month = Feb | year = 2012 | doi = 10.1002/cncy.20188 | PMID = 22162342 }}</ref> | Features:<ref name=pmid22162342>{{Cite journal | last1 = Singh | first1 = M. | last2 = Mockler | first2 = D. | last3 = Akalin | first3 = A. | last4 = Burke | first4 = S. | last5 = Shroyer | first5 = A. | last6 = Shroyer | first6 = KR. | title = Immunocytochemical colocalization of P16(INK4a) and Ki-67 predicts CIN2/3 and AIS/adenocarcinoma. | journal = Cancer Cytopathol | volume = 120 | issue = 1 | pages = 26-34 | month = Feb | year = 2012 | doi = 10.1002/cncy.20188 | PMID = 22162342 }}</ref> | ||
*p16 | *p16. | ||
*Ki-67 | **Diffuse, strong positive staining = CIN II or CIN III. | ||
**Patchy, weak positive staining = CIN I or squamous metaplasia. | |||
*Ki-67. | |||
**Several positive cells above basal layer suggests CIN II or CIN III. | |||
Notes: | Notes: | ||