Difference between revisions of "Diffuse lung diseases"
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==Non-specific interstitial pneumonia== | ==Non-specific interstitial pneumonia== | ||
*Abbreviated ''NSIP''. | *Abbreviated ''NSIP''. | ||
*Better prognosis than UIP. | |||
===General=== | |||
*Better prognosis than [[UIP]]. | |||
*Some radiologists and pathologists don't believe in this entity. | *Some radiologists and pathologists don't believe in this entity. | ||
Associations:<ref name=Ref_WMSP92>{{Ref WMSP|92}}</ref> | |||
*Connective tissue disease. | |||
*[[Rheumatoid arthritis]]. | |||
===Gross/Radiology=== | ===Gross/Radiology=== | ||
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_WMSP92>{{Ref WMSP|92}}</ref> | |||
*Fibrosis: | *Fibrosis: | ||
** | **Often uniform (unlike [[UIP]]). | ||
**"Linear fibrosis" has a good prognosis - should be mentioned in the report. | **"Linear fibrosis" has a good prognosis - should be mentioned in the report. | ||
***''Linear fibrosis'' = fibrosis that follows alveolar walls + no architectural distortion. | ***''Linear fibrosis'' = fibrosis that follows alveolar walls + no architectural distortion. | ||
*+/-Lymphoid nodules - assoc. with collagen vascular disease. | *+/-Lymphoid nodules - assoc. with collagen vascular disease. (???) | ||
*+/-Focal [[organizing pneumonia]]. | |||
Notes: | Notes: | ||
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*No honeycombing - key difference between UIP and NSIP. | *No honeycombing - key difference between UIP and NSIP. | ||
DDx: | |||
*Collagen vascular disease. | *Collagen vascular disease. | ||
*Drug reaction. | *Drug reaction. | ||
*Hypersensitivity pneumonitis (extrinic allergic alveolitis). | *[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis). | ||
==Hypersensitivity pneumonitis== | ==Hypersensitivity pneumonitis== | ||