Difference between revisions of "Chronic sialadenitis"
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'''Chronic sialadenitis''' is a chronic inflammatory process involving a [[salivary glands|salivary gland]]. | |||
'''Chronic sailolithiasis''' redirects here. | |||
'''Sialadenitis''' redirects here. | |||
==General== | |||
*Occasionally associated with malignancy, e.g. [[adenoid cystic carcinoma]].<ref name=pmid21159490>{{cite journal |author=Hasegawa M, Cheng J, Maruyama S, ''et al.'' |title=Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background |journal=Int J Oral Maxillofac Surg |volume=40 |issue=6 |pages=647–50 |year=2011 |month=June |pmid=21159490 |doi=10.1016/j.ijom.2010.11.009 |url=}}</ref> | |||
Etiology:<ref>URL: [http://emedicine.medscape.com/article/882358-overview http://emedicine.medscape.com/article/882358-overviewhttp://emedicine.medscape.com/article/882358-overview]. Accessed on: 10 January 2011.</ref> | |||
*Infection. | |||
*Autoimmune (e.g. [[Sjögren syndrome]], [[systemic lupus erythematosus]]). | |||
*Other. | |||
==Gross== | |||
Features: | |||
*Salivary gland swelling.<ref name=pmid21159490/> | |||
==Microscopic== | |||
Features: | |||
*Non-neoplastic mononuclear inflammatory infiltrate (lymphocytes, [[plasma cell]]s). | |||
*Fibrosis. | |||
*+/-Calcifications. | |||
Note: | |||
*If the infiltrate is predominantly lymphocytes Sjögren's is a possibility, and reporting a ''[[Focus score]]'' should be considered. | |||
DDx: | |||
*[[Lymphoma]] - especially [[MALT lymphoma]].<ref name=pmid22475637>{{Cite journal | last1 = Beasley | first1 = MJ. | title = Lymphoma of the Thyroid and Head and Neck. | journal = Clin Oncol (R Coll Radiol) | volume = | issue = | pages = | month = Apr | year = 2012 | doi = 10.1016/j.clon.2012.02.010 | PMID = 22475637 }}</ref> | |||
===Image=== | |||
<gallery> | |||
Image:Chronic_sialadenitis.jpg | Chronic sialadenitis. (WC/Nephron) | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
SUBMANDIBULAR GLAND, RIGHT, EXCISION: | |||
- CHRONIC SIALOADENITIS. | |||
- SIALOLITHIASIS. | |||
- TWO BENIGN LYMPH NODES. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
====Micro==== | |||
The sections show submandibular salivary gland with a mild patchy mixed mononuclear cell | |||
infiltrate, fibrosis and a large benign calcification. No zonal necrosis is identified. | |||
Significant nuclear atypia is not identified. | |||
==See also== | |||
*[[Salivary gland]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Salivary gland]] | |||
Revision as of 11:51, 2 June 2014
Chronic sialadenitis is a chronic inflammatory process involving a salivary gland.
Chronic sailolithiasis redirects here. Sialadenitis redirects here.
General
- Occasionally associated with malignancy, e.g. adenoid cystic carcinoma.[1]
Etiology:[2]
- Infection.
- Autoimmune (e.g. Sjögren syndrome, systemic lupus erythematosus).
- Other.
Gross
Features:
- Salivary gland swelling.[1]
Microscopic
Features:
- Non-neoplastic mononuclear inflammatory infiltrate (lymphocytes, plasma cells).
- Fibrosis.
- +/-Calcifications.
Note:
- If the infiltrate is predominantly lymphocytes Sjögren's is a possibility, and reporting a Focus score should be considered.
DDx:
- Lymphoma - especially MALT lymphoma.[3]
Image
Chronic sialadenitis. (WC/Nephron)
Sign out
SUBMANDIBULAR GLAND, RIGHT, EXCISION: - CHRONIC SIALOADENITIS. - SIALOLITHIASIS. - TWO BENIGN LYMPH NODES. - NEGATIVE FOR MALIGNANCY.
Micro
The sections show submandibular salivary gland with a mild patchy mixed mononuclear cell infiltrate, fibrosis and a large benign calcification. No zonal necrosis is identified. Significant nuclear atypia is not identified.
See also
References
- ↑ 1.0 1.1 Hasegawa M, Cheng J, Maruyama S, et al. (June 2011). "Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background". Int J Oral Maxillofac Surg 40 (6): 647–50. doi:10.1016/j.ijom.2010.11.009. PMID 21159490.
- ↑ URL: http://emedicine.medscape.com/article/882358-overviewhttp://emedicine.medscape.com/article/882358-overview. Accessed on: 10 January 2011.
- ↑ Beasley, MJ. (Apr 2012). "Lymphoma of the Thyroid and Head and Neck.". Clin Oncol (R Coll Radiol). doi:10.1016/j.clon.2012.02.010. PMID 22475637.